The Neurobiological Basis of Executive Function Alterations in Binge Eating Populations

Steward, Trevor; Berner, Laura A.

doi:10.1007/978-3-030-43562-2_10

Cited by 3 publications

(2 citation statements)

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“…Therefore, negative emotions like disgust may disrupt high-order cognitive processes like inhibitory control—a key feature in binge eating disorders [ 44 – 46 ]. For instance, emotions and inhibitory control share a ‘two-way connection’ between emotion processing and inhibitory control through shared brain networks (including the insula and inferior frontal gyrus) [ 47 , 48 ], which allows emotions to disrupt inhibitory control and vice versa. The insula, which is heavily implicated in interoceptive awareness, emotional processing and response inhibition, may have the ability to ‘hijack’ self-control areas of the brain and affect inhibitory control via its projections that extend to various parts of the prefrontal cortex (housing numerous regions involved in inhibition) [ 49 – 54 ].…”

Section: Introductionmentioning

confidence: 99%

“…The insula, which is heavily implicated in interoceptive awareness, emotional processing and response inhibition, may have the ability to ‘hijack’ self-control areas of the brain and affect inhibitory control via its projections that extend to various parts of the prefrontal cortex (housing numerous regions involved in inhibition) [ 49 – 54 ]. More specifically, the anterior insula acts as a “relay center” by receiving sensory information (from disgust-inducing stimuli), and subsequently modulates activity in response inhibition networks which consist of the left and right inferior and middle frontal gyri, right superior frontal gyrus, anterior cingulate cortex, anterior insula, subthalamic nucleus, pre-SMA, and dorsal aspects of the striatum [ 48 , 49 ]. Therefore, disgust sensitivity may have the ability to indirectly influence eating behaviours via its effects on self-control processes; primarily by activating the anterior insula.…”

Section: Introductionmentioning

confidence: 99%

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Disgust sensitivity and behavioural inhibitory systems in binge eating disorder: associations with eating pathology

et al. 2023

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Disgust sensitivity refers to how unpleasant a disgusting experience is to an individual and is involved in the development of many psychiatric conditions. Given its link with food ingestion, there is an interest in understanding how an individual’s susceptibility to disgust relates to dietary habits. One possible mechanism giving rise to this association is through the effects negative emotions have on high-order cognitive processes, but few studies take this model into account. The aim of this study was to characterize general disgust sensitivity in a clinical binge eating disorder (BED) population, and explore whether disgust sensitivity relates to inhibitory control and eating pathology. Following a case-controlled study design, our results show that: (1) disgust sensitivity and its subscales do not differ between BED and healthy controls, (2) higher disgust sensitivity in BED relates to greater behavioural inhibition, (3) inhibitory control reaction times relate to aspects of eating pathology, and (4) inhibitory control does not mediate relationships between disgust sensitivity and BMI among participants with BED. Understanding the role of disgust sensitivity in BED may allow us to understand how negative emotion systems maintain dysregulated eating behaviours with the potential to inform emotion-regulation treatment approaches. Level of evidence: Level III: Evidence obtained from well-designed cohort or case–control analytic studies.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Disgust sensitivity and behavioural inhibitory systems in binge eating disorder: associations with eating pathology

et al. 2023

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Neural and Behavioral Correlates of Binge Eating in 9- to 10-Year-Old Children

Smith,

Hsu,

Mason

et al. 2024

Journal of the American Academy of Child & Adolescent Psych

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The neural correlates of delay discounting in obesity and binge eating disorder

Miranda-Olivos

Steward

Martínez‐Zalacaín

et al. 2021

JBA

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Background and aimsIncreased delay discounting is associated with obesity and binge eating disorder (BED). Although BED and obesity frequently co-occur, the neural mechanisms underlying delay discounting in these conditions remain poorly understood.MethodsThirtyfive women with obesity, including 10 participants with obesity and BED and 31 controls completed a monetary delay discounting task during functional magnetic resonance imaging.ResultsWe identified that increased discounting rates were associated with decreased activity in the left anterior insula in participants with obesity compared to controls when choosing immediate rewards over delayed rewards (PFWE < 0.05). An exploratory analysis comparing the BED subsample to the other groups did not detect significant differences.Discussion and conclusionsOur findings suggest decreased activity in the anterior insula may underlie heightened delay discounting in individuals with obesity, contributing the probability of choosing immediate rewards over delayed rewards based on emotional states. Future studies including larger, more diverse samples are required to confirm these effects.

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The Neurobiological Basis of Executive Function Alterations in Binge Eating Populations

Cited by 3 publications

References 123 publications

Disgust sensitivity and behavioural inhibitory systems in binge eating disorder: associations with eating pathology

Disgust sensitivity and behavioural inhibitory systems in binge eating disorder: associations with eating pathology

Neural and Behavioral Correlates of Binge Eating in 9- to 10-Year-Old Children

The neural correlates of delay discounting in obesity and binge eating disorder

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