The neurotrophic and antineuroinflammatory effects of phenylpropanoids from Zanthoxylum nitidum var. tomentosum (Rutaceae)

Pharmacological activities of Zanthoxylum L. plants and its exploitation and utilization

“…Qin et al [ 27 ] evaluated the in vitro anti-neuroinflammatory activity of 20 phenylpropanoids isolated from various Z. nitidum using LPS-induced BV-2 microglial cells. The results revealed that four compounds exhibited significant inhibitory effects on LPS-induced NO production.…”

Comparison of production of bioactive components in Zanthoxylum nitidum taproots from different regions in southern China

“…China has abundant Z. nitidum resources, which are primarily cultivated in Guangdong and Guangxi Provinces (Lu et al, 2020; Peng et al, 2018). The root of Z. nitidum is used as medicine and has pharmacological efficacy, including anti‐inflammatory, analgesic, antibacterial, antitumor, and anticancer effects (Lin et al, 2020; Lu et al, 2020; Qin et al, 2021; Tang et al, 2017). Currently, Z. nitidum is widely used in pharmaceutical preparations and chemical industries, such as medicines for stomachache, toothache, rheumatic arthralgia and traumatic injury, as well as in toothpaste, mouthwash, shampoo, among others (Lu et al, 2020).…”

GC/MS Profile and Antifungal Activity of Zanthoxylum caribaeum Lam Essential Oil against Moniliophthora roreri Cif and Par, a Pathogen That Infects Theobroma cacao L Crops in the Tropics

“…In Colombia, it is mainly found in the Andean region, the Caribbean and part of the Amazon [2]. Some species belonging to these genera have shown a variety of biological activities such due to their high content of secondary metabolites including alkaloids, terpenes, lignans, steroids, coumarins and flavonoids, such as anti-inflammatory, anticancer, antimalarial, antioxidant, anti-HIV and antimicrobial activities [3][4][5][6][7][8]. These metabolites are distributed throughout the plant but have been found in higher concentrations in bark, roots and leaves.…”

“…Their use is emerging as a sustainable alternative for disease control in today's agriculture, where agricultural practices allow the use of certain substances to Essential oils (EOs) have a natural potential for plant defense mechanisms, are volatile compounds produced by many species, and can act against various plant pathogenic microorganisms [5]. Their use is emerging as a sustainable alternative for disease control in today's agriculture, where agricultural practices allow the use of certain substances to combat pathogens [6]. Natural products such as essential oils have emerged as an "environmentally friendly" alternative for use as effective as antimicrobial agents because they are easy to obtain and have low toxicity to non-target organisms.…”