The Neutrophil-lymphocyte ratio in patients with community-acquired pneumonia

Taboubi, A.; Toujani, S.; Khaled, S; Slim, A.; Hédhli, A.; Cheikhrouhou, S.; Ouahchi, Y.; Mjid, M.; Merai, S.

doi:10.1183/13993003.congress-2018.pa2620

Cited by 4 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous studies showed high NLR ranging from 8.27 to 31.4 in acute bacterial infections. 3,[22][23][24][25] High NLR was found in 55.3% male which is similar to one previous report. 26 According to this study, 41% gram positive isolated in blood culture presented with high NLR and 58.9% gram negative isolated in blood culture presented with high NLR.…”

Section: Discussionsupporting

confidence: 91%

See 1 more Smart Citation

Role of neutrophils to lymphocytes ratio in identification of bacterial infection in adult population

Ghouri¹,

Khurshid²,

Tariq³

et al. 2023

J Fatima Jinnah Med Univ

View full text Add to dashboard Cite

Background: Bacterial infection are difficult to distinguish from viral infection. Neutrophils are the first cells mobilize to infectious site caused by bacteria and also apoptosis of lymphocytes in response to cell mediated immunity hence raised in neutrophils and decrease in lymphocyte count. The goal of this study is to determine the neutrophil to lymphocyte ratio in patient with positive blood culture for bacteria in patients admitted in hospital. Patients and methods: This cross-sectional study was conducted at Department of Pathology, Hamdard University Karachi, Pakistan from 1st January to 31st June 2022. Total 123 adult patients with positive blood cultures admitted in ward or ICU were enrolled in the study. CBC Samples were collected from patients admitted in ward or ICU and blood culture were already sent due to clinical condition, the organism isolated in blood culture were recorded As blood culture is a gold standard investigation to detect bacterial infection .In this study we will record neutrophil to lymphocyte ratio in patients admitted with positive blood culture for bacteria. Age less than 15 years, pregnant female, OPD patients, negative blood cultures and patients on antibiotic therapy were excluded. Complete blood count (CBC) was performed in Beckman coulter model DxH 520 made by Germany. Age and ward of patient, organism isolated from blood culture, CRP. Results: A total of 123 patients with positive blood culture were enrolled in the study. Out of 123 patients 61.8% (n=76) were male and 38.2% (n=47) were female. Mean NLR was 5.9± 13.1. Total 45.5% patients presented with high NLR. Mean CRP was 58.5± 68.7. Conclusion: High NLR was seen in 45.5% which shows NLR is an important indicator of bacterial infection. More studies are needed to define true significance of NLR in all ages and negative blood cultures.

show abstract

Section: Discussionsupporting

confidence: 91%

“…Age and ward of patient, organism isolated from blood culture, CRP, neutrophil to lymphocyte ratio were recorded from patient file. Statistical analysis was performed using SPSS 25…”

Section: Methodsmentioning

confidence: 99%

Role of neutrophils to lymphocytes ratio in identification of bacterial infection in adult population

Ghouri¹,

Khurshid²,

Tariq³

et al. 2023

J Fatima Jinnah Med Univ

View full text Add to dashboard Cite

show abstract

“…Nilai NLR lebih dari 10 berkaitan dengan peningkatan resiko kematian 13,14 dan tidak berhubungan dengan nilai CURB-65. 15 Pada populasi dewasa, skor CURB-65 dan NLR berkaitan dengan resiko instabilitas klinis setelah 72 jam pasca inisiasi terapi. 16 Kombinasi CURB-65*NLR (cut off 9,06) merupakan prediktor paling signifikan dalam menentukan resiko mortalitas pada geriatric dengan pneumonia.…”

Section: Diskusiunclassified

Pengenalan Awal Pneumonia Komunitas Resiko Tinggi yang Berkembang menjadi Sepsis pada Pasien Geratri Renta: Sebuah Laporan Kasus

Aini,

Rakasiwi,

Riyatno

et al. 2024

BIKKM

View full text Add to dashboard Cite

Sepsis adalah disfungsi organ yang mengancam jiwa yang disebabkan oleh respon tubuh yang tidak teratur terhadap infeksi. Sepsis dapat terjadi akibat infeksi yang didapat komunitas atau layanan kesehatan ,dengan pneumonia terhitung lebih dari 50% kejadian sepsis pada pasien dirawat di unit perawatan intensif rumah sakit. Angka mortalitas sepsis pada geriatri dengan community-acquired pneumonia (CAP) berada antara 14% dan 26%. Pasien wanita usia 82 tahun dibawa ke IGD karena sesak napas yang memberat 1 hari sebelumnya. Pasien didiagnosis community-acquired pneumonia dengan komorbid dan status fungsional rendah yang berkembang menjadi sepsis. Pasien dirawat di unit perawatan intensif dengan memberptimbangkan skor CURB-65, PSI dan NLR. dan mendapatkan terapi cairan dan monitor balans, double antibiotic dan penanganan multidisiplin dari dokter anestesi, dokter neurologi dan dokter jantung. Setelah mendapatkan penangan optimal dan intensif, pasien meninggal pada hari ke-7 perawatan. Pneumonia dan sepsis pada pasien geriatri merupakan tantangan tersendiri yang membutuhkan pendekatan diagnosis dan resusitasi yang tepat dan cepat. Target penanganan sepsis sesegera mungkin adalah menurunkan angka mortalitas dan morbiditas pasien. Kata Kunci: Pneunomonia Komunitas, Geriatri, Renta, Sepsis

show abstract

“…5,6 Red blood cell distribution width (RDW), mean platelet volume (MPV), neutrophil and lymphocyte are cheap tests routinely used by physicians in clinical practice as part of complete blood count and RDW, MPV and neutrophil to lymphocyte ratio (NLR) are the next generation inflammatory markers associated with many diseases, indicative of systemic inflammation. [7][8][9][10] There are studies in which the severity of some infectious diseases is associated with these tests in the literature. For example; Kaya et al found that NLR and RDW levels were significantly higher in community-acquired pneumonia cases treated in the intensive care unit (ICU) compared to inpatients in the clinic, and also showed that increased NLR was associated with mortality.…”

Section: Introductionmentioning

confidence: 99%

An Easy Parameter That Can Predict Intensive Care Unit Admission in Patients with COVID-19 in the Early Stage: Neutrophil to Lymphocyte Ratio

Eke

Taşkin

Acar

et al. 2021

ijmsci

View full text Add to dashboard Cite

Background: The COVID-19 pandemic has caused more than 60 million confirmed cases and approximately 1.5 million deaths all over the world as of December 1st, 2020. So it’s important to predict the clinical course of infected patients and to prevent the disease course from worsening with early intervention. Aim: This study aimed to evaluate the new generation inflammation markers such as NLR, MPV and RDW in predicting the need for intensive care of COVID-19 patients. Methods: The retrospective cross-sectional study included 112 patients whose hemogram parameters were checked simultaneously with the diagnosis of COVID-19, hospitalized in public hospitals in Antalya province between March 16th and June 15th, 2020. Patients treated in the intensive care unit and treated only in the ward were compared according to laboratory data, and the predictive effect of study parameters on the need for intensive care was investigated. Results: Of the patients 43.8% were female and 56.3% were male. The average age was 49.48 ± 17.12 years. The percentage of patients admitted to the intensive care unit was 19.6% and, died was 5.4%. While MPV was found to be statistically significantly lower in COVID-19 patients who need intensive care, NLR and RDW were found to be statistically significantly higher. Decreased MPV and increased NLR were determined as independent risk factors for ICU admission. In addition, the optimal cut-off value was calculated as ≤ 10.4 for MPV (with 77.27% sensitivity and 66.67% specificity) and > 5.3 for NLR (with 72.73% sensitivity and 91.11% specificity) in predicting ICU admission. Conclusion: NLR, which is checked at the first admission in patients with suspected COVID-19, is an easy, fast, cheap and very valuable test in determining the severity of SARS-CoV2 infection and predicting the need for intensive care.

show abstract

The Neutrophil-lymphocyte ratio in patients with community-acquired pneumonia

Cited by 4 publications

References 0 publications

Role of neutrophils to lymphocytes ratio in identification of bacterial infection in adult population

Role of neutrophils to lymphocytes ratio in identification of bacterial infection in adult population

Pengenalan Awal Pneumonia Komunitas Resiko Tinggi yang Berkembang menjadi Sepsis pada Pasien Geratri Renta: Sebuah Laporan Kasus

An Easy Parameter That Can Predict Intensive Care Unit Admission in Patients with COVID-19 in the Early Stage: Neutrophil to Lymphocyte Ratio

Contact Info

Product

Resources

About