The Neutrophil to Lymphocyte Ratio and Serum Albumin as Predictors of Acute Kidney Injury After Coronary Artery Bypass Grafting

Abstract

Postoperative acute kidney injury (AKI) is a highly prevalent and serious complication after cardiac surgery. The aim of this study is to identify the predictors of AKI and the cut-off values after isolated off-pump coronary artery bypass grafting (OPCAB). A total of 329 adult patients, who underwent isolated OPCAB between December 2008 and February 2021, were retrospectively analyzed. The patients were divided into three groups: non-AKI, early AKI and late AKI groups. The early AKI group or the late AKI group were defined as ‘having AKI that occurred before or after 48 hours postoperatively’, respectively. Multivariate logistic regression analysis was performed to identify the predictors of AKI. Receiver operating characteristic (ROC) curve analysis was used to evaluate the cutoff value, the sensitivity, and the specificity of the predictors. On the multivariate analysis, the emergency surgery, the preoperative serum albumin, and the postoperative day 1 neutrophil to lymphocyte ratio (NL ratio) were identified as the independent predictors of AKI. However, neither albumin nor the NL ratio predicted late AKI. The present study showed the preoperative albumin and the postoperative day 1 NL ratio were the robust and independent predictors of postoperative early AKI in isolated OPCAB.

Predictive Value of Platelet-to-Albumin Ratio (PAR) for the Cardiac-Associated Acute Kidney Injury and Prognosis of Patients in the Intensive Care Unit

“…CSA-AKI is one of the most common essential consequences following CS, and the morbidity rate of CSA-AKI varies from 5% to 42% in general medicine. 23,24 Tseng et al did a retrospective analysis of 671 CS patients and discovered that the incidence of CSA-AKI was 24.3% (163/671). 25 Similarly, another monocentric study of 1900 patients with CS also demonstrated that the postoperative AKI was 49.1%.…”