The new Ru(NBD)Cl2(substituted-2,2′-biquinoline) complexes. Synthesis and characterization

Activation of human synovial mast cells from rheumatoid arthritis or osteoarthritis patients in response to aggregated IgG through Fcγ receptor I and Fcγ receptor II

“…Besides the electronic character and size of these amines determining the initiation and propagation steps, the monomer can also affect the reactions. In the present, NBD can be arranged in a chelating mode in agreement with the literature and this fact could affect the progress of the reaction 22–263); the relative areas of the signals are 1 : 1 : 6.5.…”

Dinuclear Tris(1‐pyrazolyl)methane Complexes of Ruthenium(II)

“…Indeed, each H a proton is near to the pyrazole at a cis position and falls in a strongly shielding zone the effect of which is enhanced because of the distorted coordination geometry of biq. (Due to steric hindrance, in octahedral and square planar transition metal complexes the coordination plane of biq is rotated some 20° away from the basal plane of the metal coordination polyhedron and adopts a sort of “butterfly” look with the individual quinolinic moieties subtending a dihedral angle of about 10° with respect to each other 15d…”

Synthesis of New Diversely Linked Biquinoline Derivatives by Multicomponent Imino-Diels-Alder Cycloaddition and Intramolecular Friedel-Crafts Cyclization

“…[5][6][7][8] Among the biquinolines, the 2,2¢-biquinoline framework is the best known, because of its excellent ability as ligand in coordination chemistry. [9][10][11][12][13] In addition, these compounds also represent interesting models for drug development, especially as anticancer agents. As part of our research programme on Narylimines towards the synthesis of bioactive substituted tetrahydroquinolines and quinolines, we are investigating the synthesis of small drug-like molecules containing two different quinoline nuclei, whose synthesis could be accomplished by cycloaddition and/or cyclization reactions.…”