The functional safety is a key management task, considering that public organizations have to work in the rapidly changing environment, in the conditions of growing competition in the medical sphere, and spread of influence of information technology on the development of a public organizations.The situations when administration is more interested in the impact of natural and technological aspects on the safety of an organization happens more often, while the main threats are coming from people though, and in many cases from employees. The aim is to substantiate the scientific and theoretical provisions on the essence of personnel safety of a public organizations and to establish future measures to strengthen it. We used methods of analysis and synthesis, comparative and monographic methods. The results and conclusions of our work are the management of personnel safety of a health care institution is an integral part of the personnel management system of a public organizations, aimed at identifying, neutralizing and preventing risks and threats that are associated with the use of personnel and can potentially lead to negative consequences for a public organizations. It also requires the protection of employees, the creating of favorable conditions for work, meeting needs and achieving development goals.