The novel coronavirus (SARS-CoV-2) infections in China: prevention, control and challenges

Zhang, Sheng; Diao, Meng Yuan; Duan, Liang; Lin, Zhiwei; Chen, Dechang

doi:10.1007/s00134-020-05977-9

Cited by 38 publications

(38 citation statements)

References 4 publications

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“…3). Health authorities attached great importance to epidemic and deployed disease prevention and control measures effectively [14,15]. All kinds of resources, including frontline medical staff and medical protective materials, were mobilized and deployed uniformly to guarantee patients' medical care.…”

Section: Clinical Experts-guided Hierarchical Management Strategymentioning

confidence: 99%

Lower mortality of COVID-19 by early recognition and intervention: experience from Jiangsu Province

Sun

Qiu

Huang

et al. 2020

Ann. Intensive Care

396

347

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Section: Clinical Experts-guided Hierarchical Management Strategymentioning

confidence: 99%

Lower mortality of COVID-19 by early recognition and intervention: experience from Jiangsu Province

Sun

Qiu

Huang

et al. 2020

Ann. Intensive Care

396

347

View full text Add to dashboard Cite

“…Also on that very day, the coronavirus study group of the International Committee on Taxonomy of Viruses named 2019 − nCoV as severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) [11]. Complete genomic sequences have been released by the NCBI in the last few weeks to understand the evolutionary origin and molecular 20 characteristics of this virus [12]. Ceraolo and Giorgi [13] have confirmed the high sequence similarity (> 99%) between all sequenced 2019CoVs genomes available, with the closest BCoV sequence sharing 96.2% sequence identity, confirming the notion of a zoonotic origin of 2019 − nCoV .…”

Section: Introductionmentioning

confidence: 99%

A Quantitative Genomic View of the Coronaviruses: SARS-COV2

Hassan¹,

Rout²,

Sharma³

2020

Preprint

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In 2020, the pandemic caused by the Coronaviruses (CoV) that are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV2). The Coronavirus disease (COVID-19) is a new strain that was discovered in 2019 and has not been previously identified in humans. It is the high time to investigate the quantitative and/or qualitative genomic informations of the virus SARS-CoV2 in order to strengthen the healthcare facility to fight against this viral disease. In this article, a through quantitative understanding of the purine and pyrimidine spatial distribution/organization of all 89 complete sequences of SARS-CoV (available as on date in the NCBI virus database, is made using different parameters such as fractal dimension, Hurst exponent, Shannon entropy and GC content of the nucleotide sequences of the genome of SARS-CoV2. Also a cluster among all the the SARS-CoV sequences of nucleotide have been made based on their phylogeny made through their closeness (Hamming distance) based on respective purine-pyrimidine distribution.

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“…3,4 The resistance of children to COVID-19 may be due to presence of healthy lungs and repeated exposure to different other viral pathogens that cross-protect them against COVID-19. 5,6 On December 31, 2019, the outbreak of COVID-19 was first noticed in Wuhan city, Hubei province, China, in few adults who presented with pneumonia of unexplained etiology, 7,8 and World Health Organization (WHO) declared the disease as pandemic on March 11, 2019. 9 Aggressive research efforts are currently going on to regulate this new SARS-CoV-2 outbreak in terms of therapeutic measures and vaccine development.…”

Section: Introductionmentioning

confidence: 99%

COVID-19 in Children: Present and Future Perspective, An Interim Review

Patnaik

Behera

Nayak

et al. 2020

Journal of Child Science

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Coronavirus disease 2019 (COVID-19) pandemic has affected millions of people worldwide. However, the mechanism by which the pathogen affects children is not understood completely. Children so far accounted for only1 to 6.4% of diagnosed cases and the mortality rate is also less. Though clinical findings are similar to adults, with fever and respiratory symptoms being prevalent, fewer numbers of children appear to develop severe pneumonia. Observed attenuated response to the virus may possibly be due to decrease in the expression of the angiotensin-converting enzyme 2 receptor in lungs, repeated viral exposure, and not having any underlying chronic diseases or immunosuppression. Suggested treatment included oxygen supplementation, mechanical ventilation in severe cases, nutritional support, and maintaining fluids and electrolyte balances. Although, no definitive pharmacological therapy is available, various combination of drugs like hydroxychloroquine, lopinavir/ritonavir, remdesivir, tocilizumab, and convalescent serum show promising result to an extent. As there is no specific therapeutic measure for this ailment, aggressive efforts are being made to develop a potential vaccine against the disease. Although few reports on epidemiology of COVID-19 in children have been published, comprehensive reports are lacking. The present article reviews on important issues such as epidemiological characteristics, postulations of milder disease, therapeutic aspect, and recent development of vaccination against COVID-19 in children.

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The novel coronavirus (SARS-CoV-2) infections in China: prevention, control and challenges

Cited by 38 publications

References 4 publications

Lower mortality of COVID-19 by early recognition and intervention: experience from Jiangsu Province

Lower mortality of COVID-19 by early recognition and intervention: experience from Jiangsu Province

A Quantitative Genomic View of the Coronaviruses: SARS-COV2

COVID-19 in Children: Present and Future Perspective, An Interim Review

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