Generalized Bott manifolds (over C and R) have been defined by Choi, Masuda and Suh in [4]. In this article we extend the results of [7] on the topology of real Bott manifolds to generalized real Bott manifolds. We give a presentation of the fundamental group, prove that it is solvable and give a characterization for it to be abelian.We further prove that these manifolds are aspherical only in the case of real Bott manifolds and compute the higher homotopy groups. Furthermore, using the presentation of the cohomology ring with Z 2 -coefficients, we derive a combinatorial characterization for orientablity and spin structure.