The Nutritional Status of Adult Antiretroviral Therapy Recipients with a Recent HIV Diagnosis; A Cross-Sectional Study in Primary Health Facilities in Gauteng, South Africa

Mahlangu, Khabo; Modjadji, Perpetua; Madiba, Sphiwe

doi:10.3390/healthcare8030290

Cited by 21 publications

(27 citation statements)

References 46 publications

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“…However, the nding of the study indicated the magnitude of under nutrition obtained from our study was greater than study conducted south Africa, which is (13%) (19). The discrepancy could be due to socio economic and methodological approach.…”

Section: Discussioncontrasting

confidence: 68%

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Undernutrition and associated factors among HIV-Infected adults receiving ART at Health centers, Lega Tafo and Surrounding, Ethiopia, 2021

Belcha¹

2021

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Background: Globally 38 million people were living with HIV in 2019. In Africa, 25 million people are living with HIV/AIDS undernutrition and food insecurity is endemic. Hence the study aimed to assess the magnitude of undernutrition and associated factors among HIV-infected adults receiving ART. Methods: Institutional based cross-sectional study was conducted among HIV/AIDS patients who following the ART service was selected by a simple random sampling method. The data were collected by direct interview, using a structured questionnaire. Descriptive statistics and a Logistic regression model were employed. Result: The study revealed that the magnitude of under-nutrition was 18.8%. The history of opportunistic infection (AOR=4.518:95% CI: 2.304-8.857), Patients taking ART for less than one year (AOR=3.675:95% CI: 1.831-7.377) household food insecure (AOR= 3.113:95% CI: 1.628-5.950) and dietary diversity score (AOR=2.340:95% CI: 1.221-4.485) were found to have a statistically significant association with undernutrition. Conclusion: The magnitude of undernutrition among people living with HIV/AIDS was found to be high. Having an opportunistic infection, duration of taking ART treatment, household food security status, and dietary diversity status were found to statistically significant association with undernutrition.

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Section: Discussioncontrasting

confidence: 68%

“…In this study the magnitude of under nutrition among male were. 22% while 17.5% among women, the study conducted in south Africa proved that the prevalence of under nutrition was high, according the that study prevalence of under nutrition was higher in males (18%) than females (9%) (19).…”

Section: Discussionmentioning

confidence: 79%

Undernutrition and associated factors among HIV-Infected adults receiving ART at Health centers, Lega Tafo and Surrounding, Ethiopia, 2021

Belcha¹

2021

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“…This finding is in contrast to previous studies [36,37]. However, a recent study in South Africa showed that the likelihood of an HIV patient on ART being obese was dependent on a longer duration of the treatment [43] and the type of ART administered as some ART do not promote lipogenesis. Therefore, the lack of association between ART and obesity in this study might have been affected by the duration of ART use and the type of ART administered.…”

Section: Discussioncontrasting

confidence: 86%

Relationship between Endothelial Function, Antiretroviral Treatment and Cardiovascular Risk Factors in HIV Patients of African Descent in South Africa: A Cross-Sectional Study

Nkeh-Chungag

Goswami

Engwa

et al. 2021

JCM

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Limited information on the effect of antiretroviral treatment (ART) on vascular function in South Africans of African descent living with human immunodeficiency virus (HIV) is available. The relationship between ART, vascular function and cardiovascular risk factors in South Africans of African ancestry with HIV was therefore studied. This cross-sectional study recruited 146 HIV-positive individuals on ART (HIV+ART+), 163 HIV-positive individuals not on ART (HIV+ART−) and 171 individuals without HIV (HIV−) in Mthatha, Eastern Cape Province of South Africa. Flow-mediated dilation (FMD) test was performed to assess endothelial function. Anthropometry and blood pressure parameters were measured. Lipid profile, glycaemic indices, serum creatinine as well as CD4 count and viral load were assayed in blood. Urinary albumin to creatinine ratio (ACR) was determined as a marker of cardiovascular risk. Obesity and albuminuria were positively associated with HIV, and HIV+ART+ participants had significantly higher HDL cholesterol. Dyslipidaemia markers were significantly higher in hypertensive HIV+ART+ participants compared with the controls (HIV+ART− and HIV− participants). FMD was not different between HIV+ART+ participants and the controls. Moreover, HIV+ART+ participants with higher FMD showed lower total cholesterol and LDL cholesterol comparable to that of HIV− and HIV+ART− participants. A positive relationship between FMD and CD4 count was observed in HIV+ART+ participants. In conclusion, antiretroviral treatment was associated with cardiovascular risk factors, particularly dyslipidaemia, in hypertensive South Africans of African ancestry with HIV. Although, ART was not associated with endothelial dysfunction, flow-mediated dilatation was positively associated with CD4 count in HIV-positive participants on ART.

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“…Understanding the factors associated with underweight and overweight/obesity among women of childbearing age in Nigeria and South Africa would be useful for relevant health and non-health experts to implement evidence-based and appropriate interventions to address all forms of malnutrition. This context-specific information is also important to national and international stakeholders, given the contemporary obligation to accomplish SDG 3 to end all forms of malnutrition, as well as the Global Action Plan for the Prevention and Control of NCDs target 9 to reduce the overweight/obesity burden in both countries [ 19 , 20 , 21 , 22 ]. However, there is a dearth of research on the influence of urban–rural residence on women’s body weight in Nigeria and South Africa.…”

Section: Introductionmentioning

confidence: 99%

Multilevel Analysis of Urban–Rural Variations of Body Weights and Individual-Level Factors among Women of Childbearing Age in Nigeria and South Africa: A Cross-Sectional Survey

Akokuwebe

Idemudia

2021

IJERPH

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Background: An unhealthy body weight is an adverse effect of malnutrition associated with morbidity among women of childbearing age. While there is increasing attention being paid to the body weights of children and adolescents in Nigeria and South Africa, a major surge of unhealthy body weight in women has received less attention in both countries despite its predominance. The purpose of this study was to explore the prevalence of body weights (underweight, normal, overweight, and obese) and individual-level factors among women of childbearing age by urban–rural variations in Nigeria and South Africa. Methods: This study used the 2018 Nigeria Demographic Health Survey data (n = 41,821) and 2016 South Africa Demographic Health Survey (n = 8514). Bivariate, multilevel, and intracluster correlation coefficient analyses were used to determine individual-level factors associated with body weights across urban–rural variations. Results: The prevalence of being overweight or obese among women was 28.2% and 44.9%, respectively, in South Africa and 20.2% and 11.4% in Nigeria. A majority, 6.8%, of underweight women were rural residents in Nigeria compared to 0.8% in South Africa. The odds of being underweight were higher among women in Nigeria who were unemployed, with regional differences and according to breastfeeding status, while higher odds of being underweight were found among women from poorer households, with differences between provinces and according to cigarette smoking status in South Africa. On the other hand, significant odds of being overweight or obese among women in both Nigeria and South Africa were associated with increasing age, higher education, higher wealth index, weight above average, and traditional/modern contraceptive use. Unhealthy body weights were higher among women in clustering areas in Nigeria who were underweight (intracluster correlation coefficient (ICC = 0.0127), overweight (ICC = 0.0289), and obese (ICC = 0.1040). Similarly, women of childbearing age in clustering areas in South Africa had a lower risk of experiencing underweight (ICC = 0.0102), overweight (ICC = 0.0127), and obesity (ICC = 0.0819). Conclusions: These findings offer a deeper understanding of the close connection between body weights variations and individual factors. Addressing unhealthy body weights among women of childbearing age in Nigeria and South Africa is important in preventing disease burdens associated with body weights in promoting Sustainable Development Goal 3. Strategies for developing preventive sensitization interventions are imperative to extend the perspectives of the clustering effect of body weights on a country level when establishing social and behavioral modifications for body weight concerns in both countries.

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The Nutritional Status of Adult Antiretroviral Therapy Recipients with a Recent HIV Diagnosis; A Cross-Sectional Study in Primary Health Facilities in Gauteng, South Africa

Cited by 21 publications

References 46 publications

Undernutrition and associated factors among HIV-Infected adults receiving ART at Health centers, Lega Tafo and Surrounding, Ethiopia, 2021

Undernutrition and associated factors among HIV-Infected adults receiving ART at Health centers, Lega Tafo and Surrounding, Ethiopia, 2021

Relationship between Endothelial Function, Antiretroviral Treatment and Cardiovascular Risk Factors in HIV Patients of African Descent in South Africa: A Cross-Sectional Study

Multilevel Analysis of Urban–Rural Variations of Body Weights and Individual-Level Factors among Women of Childbearing Age in Nigeria and South Africa: A Cross-Sectional Survey

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