The nutritional status of relapsing-remitting multiple sclerosis (RRMS) patients compared to that of healthy people: a Turkish hospital-based study

Efficacy of Diet on Fatigue and Quality of Life in Multiple Sclerosis

“…38,39 Burden of comorbidities is common among people with MS and the prevalence increasing, 40 likely due to the symptoms of pain, fatigue, and reduced vision, cognition, and ambulation people with MS experience 41 that increase disability burden and reduce their ability to perform activities of daily living such as acquiring and preparing healthy food. 42 Studies have shown that comorbidity burden is associated with increased risk of relapse, hospitalization, and disability progression in MS. [43][44][45] Some studies included in this NMA reported significant reductions in weight and metabolic risk factors including serum glucose and cholesterol, 46,47 supporting this possible mechanism. Despite the associations of comorbid obesity with negative outcomes in MS, recent commentaries demonstrate that considerable controversy exists in the MS field regarding the role of dietary approaches for comorbid obesity among patients with MS. 48,49 The strengths of this study include the use of NMA methods which allowed for the comparison and ranking of 8 different dietary approaches for their effect on fatigue and physical and mental QoL among people with MS and the consistency of results in analyses.…”

Opinion: The role of the registered dietitian nutritionist in multiple sclerosis care in the United States

“…People with MS have staggering healthcare costs (36) and tend to exit the workforce earlier compared to people without MS (37), suggesting that food insecurity is possibly an underappreciated consequence of living with MS. A link between disability burden and food insecurity is well documented in several groups without MS; however, this evidence is sparse among people with MS. Importantly, one study observed that people with MS shop for their own food less often compared to healthy controls (38). In addition, several observational studies have observed an inverse association between diet quality and disability burden in MS (38)(39)(40)(41), suggesting that people with the greatest disability burden likely have less ability to acquire and prepare healthy foods and likely rely more on convenience foods which tend to be less healthy.…”

“…Importantly, one study observed that people with MS shop for their own food less often compared to healthy controls (38). In addition, several observational studies have observed an inverse association between diet quality and disability burden in MS (38)(39)(40)(41), suggesting that people with the greatest disability burden likely have less ability to acquire and prepare healthy foods and likely rely more on convenience foods which tend to be less healthy. In addition, long-term food insecurity increases risk for malnutrition.…”

Overview of diet and autoimmune demyelinating optic neuritis: a narrative review

“…The infrequent incidence of MS incidence in both studies (0.2%) may underlie these null findings. In addition, cross-sectional associations of diet quality can be confounded by disability burdens that preclude acquiring and preparing healthy foods [178] . In fact, recent meta-analysis and network meta-analysis of randomized dietary intervention trials found consistent positive effects of several dietary interventions (eg Paleolithic and Mediterranean) on fatigue and QoL; however, due to the small sample size and methodological issues among the preliminary trials, the evidence had limited reliability [179,180] .…”