Compressor blade design influences aero-engine performance mainly through its total pressure ratio and efficiency. As a volume-based geometric parameterization, Free-form Deformation (FFD) brings three-dimensionality that is essential to blade design. However, the manipulation of control points with respect to simple numeric parametric perturbation renders the use of design space low-efficient. Therefore, an improved FFD with ‘wiser’ control point lay-out is expected to identify those more important design variables. This paper proposes novel design variables that are assigned to grouping of control points’ displacement in FFD lay-out. In short, the approach is realized as: (i) establish a library of sufficient blade shape samples; (ii) filter the database with geometric constraints; (iii) extract dominant modes via (POD) Proper Orthogonal Decomposition; (iv) construct new design variables and apply them in optimization. With geometric constraint filtering, problem-oriented information is injected. With POD, the dominance of new selected geometric parameters in problem description is assured. Perfunctory details of displacement data of each control point in the lay-out can be replaced by grouped data as new design variable candidates. As a proof-of-concept study of the new approach, compressor blade Rotor 37 is selected to be the good platform of testing the feasibility of POD-aided FFD as a global and flexible yet economic geometric parameterization. Result demonstrates the feasibility of proposed POD-aided FFD approach that helps conduct an optimization involving displacement of 6 × 4 × 3 control points with as few as five new design variables, while still being capable of bringing optimization effect in three test cases.