The obstetric management of preterm labour

Maresh, Michael

doi:10.1016/0957-5847(92)90020-c

Cited by 5 publications

(5 citation statements)

References 12 publications

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“…The goals of managing spontaneous preterm labour are to minimise perinatal morbidity and mortality while preserving maternal health. 4 Tocolysis has not been convincingly shown to improve neonatal outcome or survival. Administration of a full course of corticosteroids to aid fetal pulmonary maturation and in utero transfer to a specialist unit where the neonate can receive optimal care, are associated with improved outcome.…”

Section: Treatment Of Preterm Labourmentioning

confidence: 99%

Statement of Disputed Authorship

Husslein

Roura

Dudenhausen

et al. 2006

BJOG

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Section: Treatment Of Preterm Labourmentioning

confidence: 99%

Statement of Disputed Authorship

Husslein

Roura

Dudenhausen

et al. 2006

BJOG

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“…However, a recent report suggests that the technique may be of value in carefully selected cases 10 . It has been suggested that an emergency cervical cerclage should be considered only if all of the following criteria are fulfilled 11 :…”

Section: Antepartum Challengesmentioning

confidence: 99%

Problems and challenges in the management of preterm labour

McNamara

2003

BJOG

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The main problem with preterm labour is our lack of progress in the successful management of this condition. We need to reassess our approach to this problem because preterm labour is not a disease, but an event, which may result from multiple independent pathways. This problem has also been affected significantly by medical advances such as infertility treatments and changes in neonatal survival at the limit of viability. The specific challenges that we face in managing preterm labour include: problems with definition; aetiology, including genetic and infection components; diagnostic problems, such as true versus false labour and role of cervical length and fetal fibronectin; and specific interventions according to the antepartum, intrapartum and postpartum challenges. In order to address the main issue, and make future progress in the management of preterm labour, we should consider the implementation of a 'Postpartum Preterm Labour Diagnostic Workup Protocol'. These data/workup results could be entered on web-based databases for each preterm labour 'event'. An international research team could analyse data relating to specific aetiological patterns and subgroup analyses, leading to the collaborative development of 'aetiology specific' management modalities. This approach requires a close collaboration between clinicians and researchers, in order to make significant progress in this difficult area, and ultimately improve perinatal outcomes.

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“…Infants delivered preterm are susceptible to life threatening complications, such as respiratory distress syndrome, intracranial haemorrhage, necrotising enterocolitis, jaundice, hypothermia and hypoglycaemia [3] . The goal of managing spontaneous preterm labour is to minimise perinatal morbidity and mortality while preserving maternal health [4] . Improved outcomes are associated with administration of a full course of corticosteroids to aid fetal pulmonary maturation and timely in utero transfer to a higher center where the neonate can receive optimal care [5,6] .…”

Section: Introductionmentioning

confidence: 99%

“…Out of total 72 preterm new borns only 12 (16.66%) had APGAR score ≤ 7 while 60 (83.33%) had APGAR score of > 7. Table(4).…”

mentioning

confidence: 99%

Study to evaluate the efficacy and safety of Atosiban in preterm labour in North Indian population

Gupta¹,

Jahan²,

Shukla³

et al. 2023

Int. J. Clin. Obstet. Gynaecol.

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Background: Preterm birth occurs in 5-10% of all pregnancies, leading to an estimated 13 million preterm births worldwide. The goal of managing spontaneous preterm labour is to minimise perinatal morbidity and mortality while preserving maternal health. Improved outcomes are associated with administration of a full course of corticosteroids to aid fetal pulmonary maturation and timely in utero transfer to a specialist unit where the neonate can receive optimal care. Methods: A prospective, open label, non-comparative study was conducted at Ganesh Shankar vidhyarthi memorial Medical College, Kanpur in the department of obstetrics and gynaecology over a period of one year. After informed consent and ethical clearance from institutional ethics committee, Kanpur, total 72 pregnant women were recruited for this study. Eligible patients received treatment with atosiban as intravenous (I.V.) infusion for 48 hrs in three successive stages. Patients were assessed at 24 hrs, 48 hrs and 72 hrs after treatment, followed by an end of study assessment at discharge (or on the 7th day, whichever was earlier). Results: Mean age of women was 24±3.6 years and gestational age was 32 ± 2.14 weeks. In this study atosiban was successful in delaying preterm labour for ≥ 48 hours in 23.50%, ≥ 72 hours in 70.50% while 5.80% women remained undelivered for ≥ 7 days who did not require an alternate tocolytic agent or retreatment which is similar to the study of Dewan et al. where for ≥ 48 hours in 84.88% while 74.15% for ≥ 7 days, the effect of atosiban treatment on fetal health was analysed in terms of APGAR score, in which out of total 72 preterm new borns, only 12 (16.66%) had APGAR score ≤ 7 while 60 (83.33%) had APGAR score of > 7. Conclusion:The present study shows that atosiban is a safe and effective drug for the treatment of preterm labour. There were no serious maternal or fetal side effects.

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The obstetric management of preterm labour

Cited by 5 publications

References 12 publications

Statement of Disputed Authorship

Statement of Disputed Authorship

Problems and challenges in the management of preterm labour

Study to evaluate the efficacy and safety of Atosiban in preterm labour in North Indian population

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