The Occurrence of Iso 24:0 (22-Methyltricosanoic Acid) Fatty Acid in Sphingomyelin of Rat Tissues

Bettger, William J.; Blackadar, C. Brian; McCorquodale, M.L; Ewing, R. D.

doi:10.1016/s0305-0491(97)00329-5

Cited by 2 publications

(1 citation statement)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The study of SM began in the late nineteenth century, and SM was first isolated from brain tissue in the 1880s [5] and its structure characterized as N-acyl-sphingosine-1phosphorylcholine in 1927 [6]. Later, SM was isolated and characterized from many vertebrate organisms such as humans, bovines, rats, mice, and frogs [7][8][9][10], but was not isolated from invertebrates until later. SM was reported as a major phosphosphingolipid in vertebrates and a minor phosphosphingolipid in invertebrates using thin-layer chromatography (TLC) [11].…”

Section: Introductionmentioning

confidence: 99%

Biochemical Studies on Sphingolipid of Artemia franciscana (I) Isolation and Characterization of Sphingomyelin

Kojima

Inoue

Sugita

et al. 2010

Lipids

View full text Add to dashboard Cite

Sphingomyelin was isolated from cysts of the brine shrimp Artemia franciscana using QAE-Sephadex A25, Florisil and Iatrobeads column chromatographies. The chemical structure was identified using thin-layer chromatography, gas-liquid chromatography, infrared spectroscopy and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. The ceramide moiety of sphingomyelin consisted of stearic, arachidic, and behenic acids as fatty acids, and hexadeca-4- and heptadeca-4-sphingenines as sphingoids. By comparative analysis, the ceramide component of Artemia sphingomyelin appears unique in invertebrates and vertebrates. Biological functions of sphingomyelin have largely been investigated using mammalian-derived sphingomyelin. In mammals, a wide variety of molecular species of sphingomyelins have been reported, especially derived from nerve tissue, while the lower animal Artemia contains this unusual sphingomyelin perhaps because of having a much simpler nervous system. The purified unusual sphingomyelin derived from Artemia franciscana might be a very useful tool in elucidating the functions and mechanisms of action of this mediator.

show abstract

Section: Introductionmentioning

confidence: 99%