2023
DOI: 10.1016/j.scitotenv.2023.165732
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The occurrence of typical psychotropic drugs in the aquatic environments and their potential toxicity to aquatic organisms - A review

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Cited by 11 publications
(1 citation statement)
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“…Fluoxetine, a selective serotonin reuptake inhibitor widely prescribed as an antidepressant, is highly environmentally present because of human consumption. Chronic exposure to environmentally relevant concentrations of Fluoxetine (0.1, 0.5, 1, and 5 µg/L) did not alter either egg production, fertilization, and the spawning rate or the hatchability of fertilized eggs, despite increased occurrence of developmental abnormalities [ 187 ]. Although parental GSI, liver vitellogenin content, and gonadal steroidogenesis were again unaffected, an effect on steroidogenesis was evidenced by the increase in E2 plasma levels by the lowest concentration, highlighting the disruptive chemical ability of this drug [ 187 ].…”
Section: The Use Of Model Species To Investigate Reproductive Challen...mentioning
confidence: 99%
“…Fluoxetine, a selective serotonin reuptake inhibitor widely prescribed as an antidepressant, is highly environmentally present because of human consumption. Chronic exposure to environmentally relevant concentrations of Fluoxetine (0.1, 0.5, 1, and 5 µg/L) did not alter either egg production, fertilization, and the spawning rate or the hatchability of fertilized eggs, despite increased occurrence of developmental abnormalities [ 187 ]. Although parental GSI, liver vitellogenin content, and gonadal steroidogenesis were again unaffected, an effect on steroidogenesis was evidenced by the increase in E2 plasma levels by the lowest concentration, highlighting the disruptive chemical ability of this drug [ 187 ].…”
Section: The Use Of Model Species To Investigate Reproductive Challen...mentioning
confidence: 99%