The occurrence of velopharyngeal insufficiency in Pierre Robin Sequence patients

Goudy, Steven L.; Ingraham, Christopher R.; Canady, John W.

doi:10.1016/j.ijporl.2011.06.024

Cited by 32 publications

(17 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our study showed a rather high incidence of SCS, but it is nevertheless consistent with the widely ranging rates reported in PRS, 13.4% to 44.1% (Witt et al, 1997; de Buys Roessingh et al, 2008; Goudy et al, 2011; Patel et al, 2012; Stransky et al, 2013; Hardwicke et al, 2016; Morice et al, 2018). Although more precise study settings are necessary to be able to draw major conclusions and to compare the results with a similar study of the ICP population at the same cleft center (Gustafsson et al, 2018), we can see a trend toward a slightly higher overall incidence of SCS in the PRS population.…”

Section: Discussionsupporting

confidence: 92%

“…Our fistula incidence (24%) is consistent with reported rates of 0% to 26% (Witt et al, 1997; Goudy et al, 2011; Patel et al, 2012; Stransky et al, 2013; Filip et al, 2015; Morice et al, 2018) in PRS. The wide range in fistula incidence may be explained by differing cleft and maxillary characteristics.…”

Section: Discussionsupporting

confidence: 91%

“…Studies often focus on the treatment of PRS infants’ airway obstruction, with only a few examining the outcome of speech development. Results for SCS rates and fistula formation are inconsistent, and study settings are heterogeneous, comparing speech between PRS and cleft palate only (ICP) (Goudy et al, 2011; Stransky et al, 2013; Hardwicke et al, 2016) and nonsyndromic (ns-PRS) with syndromic PRS (s-PRS) (Witt et al, 1997; de Buys Roessingh et al, 2008; Patel et al, 2012). Findings are often difficult to compare because between centers the diagnostic criteria for PRS and thresholds for SCS differ.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pierre Robin Sequence: Incidence of Speech-Correcting Surgeries and Fistula Formation

Gustafsson

Vuola

Leikola

et al. 2019

The Cleft Palate-Craniofacial Journal

View full text Add to dashboard Cite

Objective: Children with Pierre Robin sequence (PRS) and cleft palate have a high rate of velopharyngeal insufficiency (VPI) following primary palatoplasty. Our purpose was to determine the long-term incidence of speech-correcting surgeries (SCSs) and fistula rates in PRS after primary palatoplasty and the influence of possible causal factors. Design: A retrospective single-center, observational chart review study. Participants: After exclusion, the study cohort comprised 78 nonsyndromic PRS children (48 females) born between 1990 and 2009 and treated at the Cleft Palate and Craniofacial Center of Helsinki University Hospital, Finland. Causal factors included gender, surgeon, age at primary palatoplasty, surgical technique, airway obstruction in infancy, and cleft severity. We analyzed the outcome at age 8 years and at data retrieval, with a median follow-up of 14 years (range: 8-27 years). Results: Thirty-four (43.6%) children received SCS by age 8 years, and of the 19 (24.4%) postoperative fistulas, 6 (7.7%) underwent closure. At data retrieval, 37 (47.4%) children had undergone SCS and 8 (10.3%) had a fistula closure. Median age at SCS was 6 years. The results showed no significant association for gender, surgeon, age at primary palatoplasty, surgical technique, cleft severity, or airway obstruction in infancy regarding incidence of SCS, fistulas, or repaired fistulas. Conclusion: Pierre Robin sequence in children is associated with a high incidence of SCS and fistula formation, which necessitates accurate clinical follow-up and observation of speech development. The development of VPI in PRS is complex and most likely involving multiple factors.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Pierre Robin Sequence: Incidence of Speech-Correcting Surgeries and Fistula Formation

Gustafsson

Vuola

Leikola

et al. 2019

The Cleft Palate-Craniofacial Journal

View full text Add to dashboard Cite

show abstract

“…Three studies 9,11,12 examined the nasal emission of both groups; one study 9 showed increased nasal emission in PRS group. The results of study 5 13 were the final results after velopharyngeal insufficiency (VPI) treatment, which was different from other studies.…”

Section: Resonancecontrasting

confidence: 66%

Do patients with isolated Pierre Robin Sequence have worse outcomes after cleft palate repair: A systematic review

Wan

Chen

Wang

2015

Journal of Plastic, Reconstructive & Aesthetic Surgery

View full text Add to dashboard Cite

“…However, the PRS group had a resonance that was significantly worse. Goudy et al (2011) found no significant difference in the need for surgical correction of VPI between a group of 21 nonsyndromic PRS patients and 42 CP-only patients. Andersson et al (2010b), however, found the incidence of pharyngoplasty among patients with CP only, treated at the CLPU-OUH, to be significantly associated with the severity of clefts.…”

Section: Discussionmentioning

confidence: 67%

Multidisciplinary Aspects of 104 Patients with Pierre Robin Sequence

Filip

Feragen²,

Lemvik³

et al. 2015

The Cleft Palate Craniofacial Journal

View full text Add to dashboard Cite

Even though the mean weight percentile for newborns with Pierre Robin sequence was low, the patients did not show a growth spurt during the first year of life. The high rate of velopharyngeal insufficiency after cleft palate repair in patients with Pierre Robin sequence needs further investigation. Also, the high rate of autism spectrum disorder among boys with Pierre Robin sequence prompts further investigation.

show abstract

The occurrence of velopharyngeal insufficiency in Pierre Robin Sequence patients

Cited by 32 publications

References 16 publications

Pierre Robin Sequence: Incidence of Speech-Correcting Surgeries and Fistula Formation

Pierre Robin Sequence: Incidence of Speech-Correcting Surgeries and Fistula Formation

Do patients with isolated Pierre Robin Sequence have worse outcomes after cleft palate repair: A systematic review

Multidisciplinary Aspects of 104 Patients with Pierre Robin Sequence

Contact Info

Product

Resources

About