Abstract. An information content analysis is used to select channels for a marine liquid cloud retrieval using the high-spectralresolution oxygen A-band instrument on NASA's Orbiting Carbon Observatory-2 (OCO-2). Desired retrieval properties are cloud optical depth, cloud pressure thickness and cloud-top pressure and the optimal channels depend on the atmospheric state, cloud properties and position within the OCO-2 swath. Based on information content criteria we select a micro-window of 75 10 of the 853 functioning OCO-2 channels spanning 763.5-764.6 nm and perform a series of synthetic retrievals with perturbed initial conditions. We estimate posterior errors from the sample standard deviations and obtain ±0.75 in optical depth, ±12.9 hPa in both cloud-top pressure and cloud pressure thickness, although removing the 10 % of samples with the highest χ 2 reduces posterior error in cloud-top pressure to ±2.9 hPa and cloud pressure thickness to ±2.5 hPa. The application of this retrieval to real OCO-2 measurements is briefly discussed, along with limitations and the greatest caution is urged regarding 15 the assumption of a single homogeneous cloud layer, which is often, but not always, a reasonable approximation for marine boundary layer clouds.