The octadecanoid signalling pathway in plants mediates a response to ultraviolet radiation

Conconi, Antonio; Smerdon, Michael J.; Howe, Gregg A.; Ryan, Clarence A.

doi:10.1038/383826a0

Cited by 223 publications

(130 citation statements)

References 27 publications

Supporting

Mentioning

122

Contrasting

Unclassified

Order By: Relevance

“…In human cells, cdc25 is also involved in the response to UV-mediated DNA damage in a p53-independent pathway, where DNA damage induces S-phase arrest via activation of Chk1 kinase, which phosphorylates cdc25A and targets it for proteasome degradation (Mailand et al, 2000). In plant cells, there is growing evidence for the role of jasmonates in UV response (Conconi et al, 1996). Some of the genes induced by jasmonates are common for UV and pathogen response, such as chalcone synthase, Phe ammonia lyase in parsley and Arabidopsis (Longemann et al, 1995;Long and Jenkins, 1998), and polyphenol oxidase, Leu aminopeptidase, Thr deaminase, and proteinase inhibitors in tomato (Lycopersicon esculentum) plants (Conconi et al, 1996).…”

Section: Discussionmentioning

confidence: 99%

“…In plant cells, there is growing evidence for the role of jasmonates in UV response (Conconi et al, 1996). Some of the genes induced by jasmonates are common for UV and pathogen response, such as chalcone synthase, Phe ammonia lyase in parsley and Arabidopsis (Longemann et al, 1995;Long and Jenkins, 1998), and polyphenol oxidase, Leu aminopeptidase, Thr deaminase, and proteinase inhibitors in tomato (Lycopersicon esculentum) plants (Conconi et al, 1996). UV exposure cannot induce mRNA expression of those genes in the tomato JL-5 mutant, defective in jasmonate synthesis, suggesting the requirement for octadecanoid compounds for a proper response (Conconi et al, 1996).…”

Section: Discussionmentioning

confidence: 99%

“…Some of the genes induced by jasmonates are common for UV and pathogen response, such as chalcone synthase, Phe ammonia lyase in parsley and Arabidopsis (Longemann et al, 1995;Long and Jenkins, 1998), and polyphenol oxidase, Leu aminopeptidase, Thr deaminase, and proteinase inhibitors in tomato (Lycopersicon esculentum) plants (Conconi et al, 1996). UV exposure cannot induce mRNA expression of those genes in the tomato JL-5 mutant, defective in jasmonate synthesis, suggesting the requirement for octadecanoid compounds for a proper response (Conconi et al, 1996). On the other hand, the levels of neither 12-oxophytodienoic acid nor JA increase after UV exposure of tomato plants (Stratmann et al, 2000), which might imply that the actual cross-talk between jasmonate signaling and UV response is downstream of jasmonates.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Differential Effect of Jasmonic Acid and Abscisic Acid on Cell Cycle Progression in Tobacco BY-2 Cells

et al. 2002

View full text Add to dashboard Cite

Environmental stress affects plant growth and development. Several plant hormones, such as salicylic acid, abscisic acid (ABA), jasmonic acid (JA), and ethylene play a crucial role in altering plant morphology in response to stress. Developmental regulation often has the cell cycle machinery among its targets. We analyzed the effect of JA and ABA on cell cycle progression in synchronized tobacco (Nicotiana tabacum) BY-2 cells. Both compounds were found to prevent DNA replication, keeping the cells in the G1 stage, when applied just before the G1/S transition. However, ABA did not have any effect on subsequent phases of the cell cycle when applied at a later stage, whereas JA effectively prevented mitosis on application during DNA synthesis. This demonstrates that JA treatment can freeze synchronized BY-2 cells in both the G1 and G2 stages of the cell cycle. Jasmonate administered after the S-phase was less effective in decreasing the mitotic index, suggesting that cell sensitivity toward JA is dependent on the cell cycle phase. In cultures detained in the G2-phase, we observed a reduced histone H1 kinase activity of kinases associated with the p13 sucl protein.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Differential Effect of Jasmonic Acid and Abscisic Acid on Cell Cycle Progression in Tobacco BY-2 Cells

et al. 2002

View full text Add to dashboard Cite

show abstract

“…The systemin signaling pathway exhibits several analogies to the animal inflammatory response such as systemin perception by a membrane-bound receptor and activation of a MAPK and a phospholipase A 2 (17)(18)(19)(20)(21)(22). UV-C radiation (Ͻ280 nm) affects the wound response in tomato plants by inducing the synthesis of proteinase inhibitors (23). Proteinase inhibitors play a role in resistance of plants to herbivorous insects.…”

mentioning

confidence: 99%

Ultraviolet-B Activates Components of the Systemin Signaling Pathway in Lycopersicon peruvianum Suspension-cultured Cells

Yalamanchili

Stratmann

2002

Journal of Biological Chemistry

View full text Add to dashboard Cite

“…P lants typically respond to environmental stress such as insect herbivory, mechanical damage, and ultraviolet (UV) irradiation by inducing defense-related proteins (1,2). Among these proteins, proteinase inhibitors I (Inh I) and II (Inh II) isolated from potato leaves are two well-characterized chymotrypsin inhibitors.…”

mentioning

confidence: 99%

Proteinase inhibitors I and II from potatoes block UVB-induced AP-1 activity by regulating the AP-1 protein compositional patterns in JB6 cells

Chen

Kaji

Bode

et al. 2001

Proc. Natl. Acad. Sci. U.S.A.

Self Cite

View full text Add to dashboard Cite

P lants typically respond to environmental stress such as insect herbivory, mechanical damage, and ultraviolet (UV) irradiation by inducing defense-related proteins (1, 2). Among these proteins, proteinase inhibitors I (Inh I) and II (Inh II) isolated from potato leaves are two well-characterized chymotrypsin inhibitors. Both proteins accumulate in potato and tomato leaves and are involved in signal transduction pathways in the plant's protective response against environmental herbivores and pathogens (3-5). In addition, these inhibitors have also been reported to have an inhibitory effect on irradiation-induced cell transformation in mammalian cells (6). We reported previously that both Inh I and Inh II block UVB-or UVC-induced transcription activator protein 1 (AP-1) activity in mouse JB6 cells (7). Considering the critical role that AP-1 activation plays in malignant cellular transformation and tumorigenesis (8-15), the inhibitory effects of these compounds on AP-1 activation may explain their reported antitumor effects. The precise mechanism explaining the inhibition is, however, unclear.AP-1 is an inducible eukaryotic transcription factor composed of products of the jun and fos oncogene families that form Jun-Jun or Jun-Fos dimers (16,17). When stimulated, AP-1 binds to specific transactivation promoter regions or TREs (12-O-tetradecanoylphorbol 13-acetate response elements) on DNA to induce transcription of genes involved in cell proliferation, metastasis, and metabolism (18). Many positive and negative components are involved in the regulation of AP-1 activity. Among these regulators, mitogen-activated protein kinase (MAP kinase) signaling pathways are common mediators of AP-1 function (19). However, we have previously observed that both Inh I and Inh II fail to block extracellular signalregulated kinases (ERKs), c-Jun N-terminal kinases (JNKs), or p38 kinase, three members of the MAP kinase family (7). This observation suggested that inhibition of AP-1 activity by Inh I and Inh II is mediated by a mechanism independent of the MAP kinase pathways.Nuclear factor B (NF B) is another eukaryotic transcriptional factor that appears to be critically involved in regulating the expression of a variety of genes that participate in the inflammatory response and suppression of apoptosis, as well as cell proliferation (20,21). Furthermore, subunits of AP-1 and NF B are able to ''cross-talk,'' and thus both transcription factors may play a role in cellular transformation (22,23). Recent reports have indicated that both AP-1 and NF B are involved in tumor promoter-induced progression in the human keratinocyte transformation model (24,25).To elucidate how the proteinase inhibitors suppress AP-1 activity and whether NF B is involved in this mechanism, we investigated changes in both AP-1 and NF B activities and DNA-binding capacities in response to cellular treatment with Inh I and Inh II and exposure to UVB, respectively. We also determined changes in the AP-1 protein composition after treatment with the Inh I and Inh I...

show abstract

The octadecanoid signalling pathway in plants mediates a response to ultraviolet radiation

Cited by 223 publications

References 27 publications

Differential Effect of Jasmonic Acid and Abscisic Acid on Cell Cycle Progression in Tobacco BY-2 Cells

Differential Effect of Jasmonic Acid and Abscisic Acid on Cell Cycle Progression in Tobacco BY-2 Cells

Ultraviolet-B Activates Components of the Systemin Signaling Pathway in Lycopersicon peruvianum Suspension-cultured Cells

Proteinase inhibitors I and II from potatoes block UVB-induced AP-1 activity by regulating the AP-1 protein compositional patterns in JB6 cells

Contact Info

Product

Resources

About