The Oral Delivery of Water‐Soluble Phenol TS‐13 Ameliorates Granuloma Formation in an In Vivo Model of Tuberculous Granulomatous Inflammation

Menshchikova, E. B.; Кожин, П. М.; Чечушков, А. В.; Khrapova, M. V.; Зенков, Н. К.

doi:10.1155/2021/6652775

Cited by 7 publications

(2 citation statements)

References 28 publications

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“…ROS are permanently generated in cells as a byproduct of respiration in mitochondria and under some physicochemical conditions [47][48][49]. There are special protective antioxidant systems against the ROS' destructive activity in a cell.…”

Section: Discussionmentioning

confidence: 99%

Ti-20Nb-10Ta-5Zr Is Biosafe Alloy for Building of Ecofriendly Greenhouse Framework of New Generation

Sarimov

Glinushkin

Sevostyanov

et al. 2022

Metals

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The search for environmentally neutral construction materials is an important aim of science from the middle of the XX century. We elaborated the method of the smelting of the new alloy Ti-20Nb-10Ta-5Zr. The Ti-20Nb-10Ta-5Zr was a β-phase alloy with an ~550 MPa yield strength, an ~700 MPa of ultimate strength and >50 GPa Young’s modulus. The Ti-20Nb-10Ta-5Zr alloy did not generate reactive oxygen species in contradistinction to the widely used NiTi. The biocompatibility of Ti-20Nb-10Ta-5Zr was studied. The human cell line cultured on the alloy showed a high mitotic index (2.2%) and a low cytotoxicity (<4% dead cells). The 30 days of the cultivation of the plants near the Ti-20Nb-10Ta-5Zr blanks did not influence the morphology and plants area. Therefore, Ti-20Nb-10Ta-5Zr may be considered as a material for the manufacture of environmentally neutral greenhouses of a new generation.

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Section: Discussionmentioning

confidence: 99%

Ti-20Nb-10Ta-5Zr Is Biosafe Alloy for Building of Ecofriendly Greenhouse Framework of New Generation

Sarimov

Glinushkin

Sevostyanov

et al. 2022

Metals

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show abstract

“…Excess ROS is normally removed during the functioning of antioxidant systems. Excessive generation of ROS, often caused by external causes, can lead to a state of "oxidative stress" that is dangerous for the integrity and functioning of cells [23,52,53]. At the cellular level, it can lead to mutagenesis, protein inactivation, lipid peroxidation, etc., [54].…”

Section: Discussionmentioning

confidence: 99%

The Development of New Nanocomposite Polytetrafluoroethylene/Fe2O3 NPs to Prevent Bacterial Contamination in Meat Industry

et al. 2022

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The bacterial contamination of cutting boards and other equipment in the meat processing industry is one of the key reasons for reducing the shelf life and consumer properties of products. There are two ways to solve this problem. The first option is to create coatings with increased strength in order to prevent the formation of micro damages that are favorable for bacterial growth. The second possibility is to create materials with antimicrobial properties. The use of polytetrafluoroethylene (PTFE) coatings with the addition of metal oxide nanoparticles will allow to the achieving of both strength and bacteriostatic effects at the same time. In the present study, a new coating based on PTFE and Fe2O3 nanoparticles was developed. Fe2O3 nanoparticles were synthesized by laser ablation in water and transferred into acetone using the developed procedures. An acetone-based colloidal solution was mixed with a PTFE-based varnish. Composites with concentrations of Fe2O3 nanoparticles from 0.001–0.1% were synthesized. We studied the effect of the obtained material on the generation of ROS (hydrogen peroxide and hydroxyl radicals), 8-oxoguanine, and long-lived active forms of proteins. It was found that PTFE did not affect the generation of all the studied compounds, and the addition of Fe2O3 nanoparticles increased the generation of H2O2 and hydroxyl radicals by up to 6 and 7 times, respectively. The generation of 8-oxoguanine and long-lived reactive protein species in the presence of PTFE/Fe2O3 NPs at 0.1% increased by 2 and 3 times, respectively. The bacteriostatic and cytotoxic effects of the developed material were studied. PTFE with the addition of Fe2O3 nanoparticles, at a concentration of 0.001% or more, inhibited the growth of E. coli by 2–5 times compared to the control or PTFE without NPs. At the same time, PTFE, even with the addition of 0.1% Fe2O3 nanoparticles, did not significantly impact the survival of eukaryotic cells. It was assumed that the resulting composite material could be used to cover cutting boards and other polymeric surfaces in the meat processing industry.

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Berberine Alleviates the Damage, Oxidative Stress and Mitochondrial Dysfunction of PC12 Cells Induced by High Glucose by Activating the KEAP1/Nrf2/ARE Pathway

Yuan

Wang²,

Zicheng³

et al. 2023

Mol Biotechnol

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The Oral Delivery of Water‐Soluble Phenol TS‐13 Ameliorates Granuloma Formation in an In Vivo Model of Tuberculous Granulomatous Inflammation

Cited by 7 publications

References 28 publications

Ti-20Nb-10Ta-5Zr Is Biosafe Alloy for Building of Ecofriendly Greenhouse Framework of New Generation

Ti-20Nb-10Ta-5Zr Is Biosafe Alloy for Building of Ecofriendly Greenhouse Framework of New Generation

The Development of New Nanocomposite Polytetrafluoroethylene/Fe2O3 NPs to Prevent Bacterial Contamination in Meat Industry

Berberine Alleviates the Damage, Oxidative Stress and Mitochondrial Dysfunction of PC12 Cells Induced by High Glucose by Activating the KEAP1/Nrf2/ARE Pathway

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