The Oral-Dental Findıngs of Patients Treated with Antineoplastic Treatments Targeting Non-Head and Neck Tumors in Childhood

Abstract

Aim: This study investigates oral complications in pediatric oncology patients undergoing antineoplastic treatments for non-head and neck tumors, with a focus on their impact on tooth development.
 Method: Twenty pediatric patients (aged 3 to 14) undergoing chemotherapy for non-head and neck tumors were examined clinically. Oral and perioral tissues were assessed, and specific complications were documented. Patient records were retrospectively reviewed to identify pre-existing oral issues.
 Results: The study revealed significant oral complications associated with antineoplastic treatments, including enamel defects (60%), gingivitis (60%), delayed apexification (55%), and mucositis (30%). Additional complications such as lymphadenopathy, delayed eruption, and herpes simplex infection were also observed.
 Conclusion: Antineoplastic treatments for non-head and neck tumors in pediatric patients can significantly affect tooth development, leading to various oral complications. Early detection and management of these complications are vital for treatment continuity and enhancing the quality of life for pediatric oncology patients.