The oral microbial odyssey influencing chronic metabolic disease

Gupta, Upasana; Dey, Priyankar

doi:10.1080/13813455.2023.2296346

Cited by 5 publications

(2 citation statements)

References 161 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recent evidence now suggests that oral and gut microflora may have significant impacts on the predisposition, development, and stability of obesity in adults over time [ 7 , 8 ]. Most of the focus of these investigations has been on the two-way relationships between the oral microbiome and periodontal disease with inflammation, cardiovascular disease, and obesity [ 9 , 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Higher Prevalence of the Periodontal Pathogen Selenomonas noxia among Pediatric and Adult Patients May Be Associated with Overweight and Obesity

Williams,

Porter,

Kingsley

et al. 2024

Pathogens

View full text Add to dashboard Cite

New evidence has suggested that oral and gut microflora may have significant impacts on the predisposition, development, and stability of obesity in adults over time—although less is known about this phenomenon in children. Compared with healthy-weight controls, overweight and obese adult patients are now known to harbor specific pathogens, such as Selenomonas noxia (S. noxia), that are capable of digesting normally non-digestible cellulose and fibers that significantly increase caloric extraction from normal dietary intake. To evaluate this phenomenon, clinical saliva samples (N = 122) from subjects with a normal BMI (18–25) and a BMI over 25 (overweight, obese) from an existing biorepository were screened using qPCR. The prevalence of S. noxia in samples from normal-BMI participants were lower (21.4%) than in overweight-BMI (25–29; 46.1%) and obese-BMI (30 and above; 36.8%) samples—a strong, positive correlation that was not significantly affected by age or race and ethnicity. These data strongly suggest that S. noxia may be intricately associated with overweight and obesity among patients, and more research will be needed to determine the positive and negative feedback mechanisms that may be responsible for these observations as well as the interventions needed to remove or reduce the potential effects of this oral pathogen.

show abstract

Section: Introductionmentioning

confidence: 99%

Higher Prevalence of the Periodontal Pathogen Selenomonas noxia among Pediatric and Adult Patients May Be Associated with Overweight and Obesity

Williams,

Porter,

Kingsley

et al. 2024

Pathogens

View full text Add to dashboard Cite

show abstract

“…The health effects of the Japanese and Mediterranean diets are also mediated through the gut microbiota [ 10 , 11 ]. Moreover, the oral microbiota is also known to affect the development and progression of systemic diseases such as cardiovascular disease, diabetes, liver disease, and dementia, and the oral microbiota is also associated with dietary patterns [ 12 , 13 , 14 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

A Cohort Study of the Influence of the 12-Component Modified Japanese Diet Index on Oral and Gut Microbiota in the Japanese General Population

Sato,

Chinda,

Iino

et al. 2024

Nutrients

View full text Add to dashboard Cite

The Japanese diet is a healthy dietary pattern, and the oral or gut microbiota have been identified as the main factors underlying the beneficial effects of the Japanese diet. However, epidemiological studies on Japanese dietary patterns calculated from daily eating habits in the general population yielded inconsistent findings. This study aimed to determine the association between the 12-component modified Japanese Diet Index (mJDI12) and the oral and gut microbiota in the general population of a rural area in Japan. After propensity-score matching, 396 participants (198 each in the low and high mJDI12 groups) were picked out. One year after the follow up survey, we reclassified the subjects and compared the low and high mJDI12 groups again. Participants with a high mJDI12 had a higher relative abundance of butyric acid-producing bacteria in their gut microbiota. Moreover, the significantly higher dietary fiber intake in the high mJDI12 group suggested that the high intake of dietary fiber contributed to an increase in butyric acid-producing bacteria in the gut. In contrast, in individuals with a high mJDI12, only Allpprevotella was decreased in the oral microbiota. Thus, the Japanese dietary pattern can have beneficial effects by improving the oral and gut microbiota.

show abstract

Gut microbiota-centered risk factors and altered immunometabolism in the pathogenesis and prophylaxis of Clostridium difficile infection

Saeed,

Batra,

Rezgui

et al. 2024

Journal of King Saud University - Science

View full text Add to dashboard Cite

The oral microbial odyssey influencing chronic metabolic disease

Cited by 5 publications

References 161 publications

Higher Prevalence of the Periodontal Pathogen Selenomonas noxia among Pediatric and Adult Patients May Be Associated with Overweight and Obesity

Higher Prevalence of the Periodontal Pathogen Selenomonas noxia among Pediatric and Adult Patients May Be Associated with Overweight and Obesity

A Cohort Study of the Influence of the 12-Component Modified Japanese Diet Index on Oral and Gut Microbiota in the Japanese General Population

Gut microbiota-centered risk factors and altered immunometabolism in the pathogenesis and prophylaxis of Clostridium difficile infection

Contact Info

Product

Resources

About