During the Late Glacial, hunter-gatherers began using ceramic cooking containers in three separate geographic regions of East Asia: China, Japan and along the Amur River in the Russian Far East.While recent research has clarified the use of early pottery in Japan, very little is known about what led to the emergence of pottery in the other two areas, including the likely environmental, economic or cultural drivers. In this paper we focus on the Russian Far East, where pottery has been recovered from dated contexts that span circa 16,200 to 10,200 years ago (cal BP). Interpreting the use of early pottery along the Amur River has been difficult because the region's acidic soils make palaeo-economic reconstructions challenging. To address this gap in knowledge we undertook lipid residue analysis of 28 pot sherds from the sites of Khummi, Gasya, and Goncharka 1 on the Lower Amur River, and the Gromatukha site on the Middle Amur. Our results indicate that pottery was employed to process aquatic oils at sites on the Lower Amur, a pattern of use that aligns with similar results from Japan, and suggests that fishing -probably of salmonids and freshwater fish -was becoming increasingly important during this period. In contrast, the results from the Middle Amur indicate a different pattern showing a significant contribution of ruminant animals. These regional differences in use are also mirrored in contrasting manufacturing techniques with pottery from the Middle and Lower Amur forming distinct ceramic traditions. These combined insights may point to greater local variability in the development and use of early pottery in East Asia than has previously been indicated.