I describe the plans, flows, key facilities, test beds, pathfinders, simulators, and ground support equipment that could be used to fully integrate, functionally test, and qualify the Origins Space Telescope (Origins). The Origins observatory consists of the spacecraft bus module and the cryogenic payload module, which comprises the telescope and three science instruments. The telescope is a three-mirror anastigmat and is composed of four mirrors: three with optical power (the elliptical primary, hyperbolic secondary, and elliptical tertiary mirrors) and a flat field-steering mirror. The three science instruments spanning the wavelength range 2.8 to 588 μm provide the powerful new spectroscopic and imaging capabilities required to achieve the scientific objectives. The Origins Survey Spectrometer uses six gratings in parallel to take multibeam spectra simultaneously across the 25-to 588-μm window through long slits enabling deep three-dimensional extragalactic surveys. The far-IR imager/polarimeter provides imaging and polarimetric measurement capabilities at 50 and 250 μm. Its fast mapping enables rapid follow-up of transient or variable sources and efficient monitoring campaigns. The mid-infrared spectrometer simultaneously provides spectroscopy over 2.8 to 20 μm with exquisite stability and precision (<5 ppm between 2.8 and 10 μm, <20 ppm between 11 to 20 μm). All the instruments are delivered for integration and test fully qualified and calibrated. The integration and test program implemented at each level of assembly is discussed as well as the separation of thermal vacuum testing between the hot and cold zones of the observatory. © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.