Fracture of the os peroneum is rare, and displacement of the fracture can be indicative of a tear in the peroneal longus tendon. A fifth metatarsal base fracture is a common injury caused by sudden inversion and plantar flexion of the hindfoot. We observed a rare case of a fifth metatarsal base zone I fracture combined with a displaced os peroneum fracture in a 34-year-old woman. The patient was treated with resection of the os peroneum and repair of the peroneal longus tendon, as well as open reduction and internal fixation of the fifth metatarsal base. After exposing the fragment of the fifth metatarsal base, the distal part of the fractured os peroneum was found to be located just under the fracture site. There were no complications or discomfort of the foot or ankle at 2 years postoperatively. Resection of the os peroneum and direct repair of the peroneal longus tendon were easily performed after the fifth metatarsal base fragment was exposed. This was an innovative method for performing peroneal longus tendon repair in the deep portion of the midfoot.T he os peroneum is an accessory ossicle of the peroneal longus tendon that is located around the peroneal tunnel of the cuboid bone; it was reported to exist in 5% to 45% of individuals and be bilateral and symmetrical in most cases. 1-5 A bipartite appearance is a frequent finding, occurring in approximately 30% of adults with an os peroneum injury. 6 Os peroneum injury has been previously reported and can be caused by supination and plantar-flexion forces, which can cause tensile loading across the os peroneum. [7][8][9] Treatment includes excision of the bone fragments with direct repair of the tendon and tenodesis of the peroneal longus to the brevis or cuboid. 10-12 A fifth metatarsal base fracture is a common injury caused by sudden inversion and plantar flexion of the hindfoot, which generates tension at the insertion of the lateral band of the plantar aponeurosis. [13][14][15] According to the fracture site, these fractures are classified into three zones. Zone I comprises the most proximal part of the tuberosity of the fifth metatarsal and includes the insertion of the peroneus brevis tendon, the peroneus tertius, and the lateral band of the plantar aponeurosis. Zone I fractures are the most common and tend to heal reliably with conservative treatment. [16][17][18]