The outbreak of Coronavirus Disease 2019 (COVID-19)—An emerging global health threat

Ali, Shajeea Arshad; Baloch, Mariam; Ahmed, Naseem; Ali, Asadullah Arshad; Iqbal, Ayman

doi:10.1016/j.jiph.2020.02.033

Cited by 308 publications

(205 citation statements)

References 7 publications

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“…As of April 22, 2,594,835 confirmed cases of COVID-19, and 181,170 deaths were reported worldwide [6]. The intensity of the catastrophic effects of COVID-19 is equally faced by developing and developed nations; however, the situation could be worse in countries with fragile healthcare systems [7,8].…”

Section: Introductionmentioning

confidence: 99%

View of Pakistani Residents toward Coronavirus Disease (COVID-19) during a Rapid Outbreak: A Rapid Online Survey

Hayat

Rosenthal

et al. 2020

IJERPH

100

111

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Background: Coronavirus disease (COVID-19) is a deadly disease that is affecting most of the countries worldwide. Public understanding, including knowledge about signs and symptoms, mode of transmission, and hygiene of COVID-19, is vital for designing effective control strategies during a public health crisis. The current study is aimed at investigating the public's perspective about COVID-19, including their knowledge, attitude, and practices. Methods: A rapid online survey comprising 22 items was administered during the rapid outbreak of COVID-19 in Pakistan. Questions were focused on the prevention, transmission, clinical features, and control of COVID-19. In addition, the attitudes and practices of the participants were explored. Descriptive statistics, Mann-Whitney tests, Kruskal-Wallis tests, and regression analysis were carried out during data analysis. Results: A total of 1257 respondents participated in this study. Most of the respondents had good knowledge (good = 64.8%, average = 30.5%, poor = 4.7%) of COVID-19. Gender, marital status, education, and residence were observed to have a significant association with the knowledge score. A vast majority of the survey respondents (77.0%) believed that COVID-19 would be controlled successfully in Pakistan. The practices of wearing a mask (85.8%) and handwashing (88.1%) were common among the participants. Conclusion: The participants demonstrated good knowledge and reasonable attitudes and practices toward most aspects of the COVID-19 outbreak. Improvements in certain areas could be made by mass-level education.

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Section: Introductionmentioning

confidence: 99%

View of Pakistani Residents toward Coronavirus Disease (COVID-19) during a Rapid Outbreak: A Rapid Online Survey

Hayat

Rosenthal

et al. 2020

IJERPH

100

111

View full text Add to dashboard Cite

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“…A few individuals tainted with the SARS-COV-2 infection feel alright, whereas othersindeed those who are sound and moderately youthfulget exceptionally ill. The COVID-19 widespread seem have tainted 90% of the world populace and slaughtered more than 40.6 million individuals in the event that no moderation measures were put in place to combat it by the individual states all inclusive (Agarwal et al, 2020;Ai et al, 2020;Arshad Ali et al, 2020). As labs closed down, universally a few thousand researchers are redeploying to battle crown infection.…”

Section: Introductionmentioning

confidence: 99%

Understanding the binding affinity of noscapines with protease of SARS-CoV-2 for COVID-19 using MD simulations at different temperatures

Kumar

Kumari

Jayaraj

et al. 2020

Journal of Biomolecular Structure and Dynamics

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The current outbreak of a novel coronavirus, named as SARS-CoV-2 causing COVID-19 occurred in 2019, is in dire need of finding potential therapeutic agents. Recently, ongoing viral epidemic due to coronavirus (SARS-CoV-2) primarily affected mainland China that now threatened to spread to populations in most countries of the world. In spite of this, there is currently no antiviral drug/ vaccine available against coronavirus infection, COVID-19. In the present study, computer-aided drug design-based screening to find out promising inhibitors against the coronavirus (SARS-CoV-2) leads to infection, COVID-19. The lead therapeutic molecule was investigated through docking and molecular dynamics simulations. In this, binding affinity of noscapines(23B)-protease of SARS-CoV-2 complex was evaluated through MD simulations at different temperatures. Our research group has established that noscapine is a chemotherapeutic agent for the treatment of drug resistant cancers; however, noscapine was also being used as anti-malarial, anti-stroke and cough-suppressant. This study suggests for the first time that noscapine exerts its antiviral effects by inhibiting viral protein synthesis. ARTICLE HISTORY

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“…The COVID-19 attacked both global public-health and economy, and hence the Public Health Emergency of International Concern (PHEIC) has been established by the World Health Organization (WHO) with strategic objectives to curtail its negative impact on 30 January 2020 [1]. However, the number of Confirmed COVID-19 Cases is exponentially increasing in many countries and onboard the cruises ships [2][3][4][5][6], so that it is a challenge to minimize the risk from COVID-19 and a systematic review is absolutely necessary. To date, no specific antiviral On the other hand, Chinese people have significantly contributed to the epidemic prevention and control, and WHO also agreed with their efforts in this outbreak [8].…”

Section: Introductionmentioning

confidence: 99%

From SARS to COVID-19: A Bibliometric study on Emerging Infectious Diseases with Natural Language Processing technologies

Hu¹,

Chen²,

Wang³

et al. 2020

Preprint

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[Background] On January 7, 2020, the novel coronavirus named "COVID-19" aroused worldwide concern was identified by Chinese scientists. Many related research works were developed for the emerging, rapidly evolving situation of this epidemic. This study aimed to analyze the research literatures on SARS, MERS and COVID-19 to retrieve important information for virologists, epidemiologist and policy decision makers. [Methods] In this study, we collected data from multi data sources and compared bibliometrics indices among COVID-19, Severe Acute Respiratory Syndrome (SARS), and Middle East Respiratory Syndrome (MERS) up to March 25, 2020. In purpose to extract data in corresponding quantity and scale, the volume of search results will be balance with the limitation of publication years. For further analysis, we extracted 1,480 documents from 1,671 candidates with Natural Language Processing technologies. [Results] In total, 13,945 research literatures of 7 datasets were selected for analysis. Unlike other topics, research passion on epidemic may reach its peak at the first year the outbreak happens. The document type distribution of SARS, MERS and COVID-19 are nearly the same (less than 6 point difference for each type), however, there were notable growth in the research qualities during these three epidemics (3.68, 6.63 and 11.35 for Field-Weighted Citation Impact scores). Asian countries has less international collaboration (less than 35.1\%) than the Occident (more than 49.5\%), which should be noticed as same as research itself. [Conclusions] We found that research passion on epidemics may always reach its peak at the first year after outburst, however, the peak of research on MERS appeared at the third year because of its outburst of reproduction in 2015. For the research quality, although we did better in research qualities than before especially on COVID-19, research on epidemics not started from our own country should not be looked down. Another important effective strategy for enhancing epidemic prevention for China and other Asian countries is to continue strengthening international collaboration.

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The outbreak of Coronavirus Disease 2019 (COVID-19)—An emerging global health threat

Cited by 308 publications

References 7 publications

View of Pakistani Residents toward Coronavirus Disease (COVID-19) during a Rapid Outbreak: A Rapid Online Survey

View of Pakistani Residents toward Coronavirus Disease (COVID-19) during a Rapid Outbreak: A Rapid Online Survey

Understanding the binding affinity of noscapines with protease of SARS-CoV-2 for COVID-19 using MD simulations at different temperatures

From SARS to COVID-19: A Bibliometric study on Emerging Infectious Diseases with Natural Language Processing technologies

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