The Outcome of Diverticulosis in Kidney Recipients With Polycystic Kidney Disease

Pourfarziani, Vahid; Mousavi-Nayeeni, S.-M.; Ghaheri, Hafez; Assari, Shervin; Saadat, Seyed Hassan; Panahi, F; Noorbala, M.-H.; Vasei, A.; Norouzi, Abbas; Simforoosh, N.

doi:10.1016/j.transproceed.2007.02.007

Cited by 45 publications

(43 citation statements)

References 6 publications

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“…4,12,15 The incidence of progression to diverticulitis with or without perforation in these 3 studies was approximately 16% (7/45) over various periods of followup. Sawyerr et al 12 Two studies examined the incidence of diverticulitis among 128 patients who were known not to have diverticulosis before transplantation.…”

Section: Findings From Included Studiesmentioning

confidence: 94%

“…22 Four studies examined a mixture of patients with perforated and nonperforated diverticulitis. 4,6,14,19 These 4 studies did not specify which signs or symptoms were associated with the perforated vs the nonperforated group; thus, we were unable to distinguish the signs and symptoms between perforated diverticulitis and nonperforated diverticulitis. These studies found that approximately 89% (31/35) of patients presented with abdominal pain, 75% (6/8) with leukocytosis, 61% (14/23) with fevers, 54% (19/ 35) with abdominal tenderness, and 50% (5/10) with hypotension.…”

Section: Findings From Included Studiesmentioning

confidence: 99%

“…4 -6 The increased mortality from diverticulitis has been postulated to result from a combination of delays in diagnosis and the decreased ability of immunosuppressed patients to limit the spread of infection. 4,7 The population of immunocompromised individuals is large and growing. At the end of 2006, there were an estimated 1.1 million people living in the United States with HIV or AIDS.…”

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confidence: 99%

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Diverticulitis in Transplant Patients and Patients on Chronic Corticosteroid Therapy: A Systematic Review

Hwang

Cannom

Abbas

et al. 2010

Diseases of the Colon &Amp; Rectum

120

110

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Section: Findings From Included Studiesmentioning

confidence: 94%

Section: Findings From Included Studiesmentioning

confidence: 99%

mentioning

confidence: 99%

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Diverticulitis in Transplant Patients and Patients on Chronic Corticosteroid Therapy: A Systematic Review

Hwang

Cannom

Abbas

et al. 2010

Diseases of the Colon &Amp; Rectum

120

110

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“…Whereas here too there are few data for hypertension and kidney diseases, there are numerous studies on the risk constellation of diverticular diseases and immunosuppression [26,27,28]. …”

Section: Influencing Factorsmentioning

confidence: 99%

Diverticular Disease: Guidelines of the German Society for Gastroenterology, Digestive and Metabolic Diseases and the German Society for General and Visceral Surgery

Kruis

Germer²,

Leifeld³

et al. 2014

Digestion

134

117

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Background: Diverticular disease is one of the most common disorders of the gastrointestinal tract. 28-45% of the population develop colonic diverticula, while about 25% suffer symptoms and about 5% complications. Aim: To create formal guidelines for diagnosis and management. Methods: Six working groups with 44 participants analyzed key questions in subject areas assigned to them. Following a systematic literature search, 451 publications were included. Consensus was obtained by agreement within the working groups, two Delphi processes and a guideline conference. Results: Targeted management of diverticular disease requires a classificatory diagnosis. A new classification was created. In addition to the clinical examination, intestinal ultrasound or computed tomography is the determining factor. Interval colonoscopy is recommended to exclude comorbidities. A low-fiber diet, obesity, lack of exercise, smoking and immunosuppression have an adverse impact on diverticulosis. This can lead to diverticulitis. Antibiotics are no longer recommended in uncomplicated diverticulitis if no risk factors such as immunosuppression are present. If close monitoring is ensured, uncomplicated diverticulitis can be treated on an outpatient basis. Complicated diverticulitis should be treated in hospital, involving broad-spectrum antibiotic therapy, where necessary abscess drainage, and surgery, if possible laparoscopically. In the case of chronic relapsing diverticulitis, the risk of perforation decreases with each episode, so that surgery is no longer recommended after the second episode but only following individual assessment. Conclusions: New findings on diverticular disease call into question the overuse of antibiotics and excessive indications for surgery. Targeted treatment requires a precise diagnosis and intensive interdisciplinary cooperation. i 2014 S. Karger AG, Basel

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“…Diverticulitis with or without perforation occurred in 6% of patients, with 57% of these patients having ADPKD. 15,19,20 In a very recent report, Scotti and associates 4 described a series of 17 transplant patients with diverticular disease; 47% of these patients had ADPKD. The incidence of perforation was 1.25%, with 44% of these afflicted with ADPKD.…”

Section: Discussionmentioning

confidence: 99%

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Kakavia

Moris²,

Karatza³

et al. 2016

Exp Clin Transplant

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Results: One patient died from septic shock before any surgery, and 3 patients died during the early postoperative period, resulting in a morality rate of 36.3%. All patients who died had a functioning graft. From the patients who were discharged, the mean follow-up was 16 months (range, 4-32 months). Conclusions: Intestinal perforation after renal transplant is a major and potentially lethal complication. Clinical presentation is usually equivocal, and the transplant surgeon should be highly suspicious when treating a renal transplant recipient with acute abdominal pain, even in cases without other predisposing factors (diverticulitis, ischemic colitis, and so forth), so that this condition could be investigated and unmasked.

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The Outcome of Diverticulosis in Kidney Recipients With Polycystic Kidney Disease

Cited by 45 publications

References 6 publications

Diverticulitis in Transplant Patients and Patients on Chronic Corticosteroid Therapy: A Systematic Review

Diverticulitis in Transplant Patients and Patients on Chronic Corticosteroid Therapy: A Systematic Review

Diverticular Disease: Guidelines of the German Society for Gastroenterology, Digestive and Metabolic Diseases and the German Society for General and Visceral Surgery

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