The outcome of surgery for colorectal cancer in the elderly: a 12-year review from the Trafford database

Kingston, R. D.; Jeacock, Julie; Walsh, S.; Keeling, F

doi:10.1016/s0748-7983(95)97009-6

Cited by 45 publications

(30 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, there were no significant differences either in the overall rate of local complications (infection of the surgical wound, anastomotic fistulae or intra-abdominal abscesses) or when rates of such complications were analysed separately. These findings agree with those of other authors (6,20,21,(25)(26)(27)(28)(29).…”

Section: Discussionsupporting

confidence: 94%

See 1 more Smart Citation

Colorectal cancer in the elderly: characteristics and short term results

Arenal-Vera¹,

Tinoco-Carrasco²,

del-Villar-Negro

et al. 2011

Rev. esp. enferm. dig.

View full text Add to dashboard Cite

Objective: to analyse the characteristics of colorectal cancer in elderly patients and to assess the outcomes of treatment.Materials and methods: the study included 1924 patients diagnosed with colorectal cancer during a 22 year period . We analysed patient clinical and demographic characteristics as well as their treatment and its outcome.Results: there was an increase in emergency surgery with age, increasing from 13% among patients under 80 years of age to 47% in those over 90 years of age (p = 0.0001). On the other hand, the overall percentage of patients who underwent surgical treatment decreased from 96% in patients younger than 80 years of age, to 85% and 59% in octogenarians and nonagenarians, respectively (p = 0.0001), and there was a similar pattern in the rates of curative surgery among patients who underwent surgery. The overall mortality of patients who underwent surgery was 8% (141 out of 1,769), increasing from 4% in patients younger than 70 years of age to 25% in those over 90 (p = 0.0001). Multivariate analysis showed that the factors associated with mortality were the emergency nature of the surgery (p = 0.001), the ASA grade (p = 0.0001), and the presence of systemic complications (p = 0.0001), the weight of age decreasing significantly with respect to the univariate analysis (p = 0.013).Conclusions: there is an increase in the rate of complicated forms of colorectal cancer with increasing age of patients. In addition, there is a dramatic decrease in the rate of curative tumour resection with increasing age. Intraoperative mortality for colorectal cancer in octogenarians and nonagenarians is more closely related to the nature and intent of the surgery (elective or emergency; palliative or curative), the perioperative risk (ASA grade), and severe systemic complications, than to age.

show abstract

Section: Discussionsupporting

confidence: 94%

“…The increase in cancers of the right colon and the decrease in the prevalence of rectal cancer in elderly patients are well known (15,20,21). This difference in tumour location explains the lower prevalence of rectal haemorrhage and tenesmus with increasing age, evident in our study.…”

Section: Discussionsupporting

confidence: 72%

Colorectal cancer in the elderly: characteristics and short term results

Arenal-Vera¹,

Tinoco-Carrasco²,

del-Villar-Negro

et al. 2011

Rev. esp. enferm. dig.

View full text Add to dashboard Cite

show abstract

“…Increasing age remains a prognostic variable for diseasefree survival on multivariate analysis including other known factors such as stage, tumor grade and preoperative CEA level. This is in contrast to other studies that have demonstrated similar survival outcomes for elderly patients who undergo surgical treatment of colorectal cancer once other variables are stratified [8][9][10]. In fact, Violi et al analyzed disease-related survival when corrected for age (adjusting for the impact of co-morbid disease on survival) and found that age did not correlate with survival outcome from colorectal cancer [11].…”

contrasting

confidence: 59%

Re: Rectal cancer surgery in the elderly: A multivariate analysis of outcome risk factors, by Bufalari A, Giustozzi G, Burattini MF, et al.

Bold

2006

Journal of Surgical Oncology

View full text Add to dashboard Cite

“…Kolorektales Karzinom · Lymphadenektomie · Alterschirurgie Bedingt durch einen stetig wachsenden Anteil älterer Menschen kommt es in den westlichen Industrieländern zu einer Zunahme Hochbetagter mit kolorektalem Karzinom [4,5,11,14,16,18,22]. Kein Zweifel besteht, dass auch für diese Altersgruppe die Resektion die Therapie der Wahl darstellt.…”

Section: Schlüsselwörterunclassified