“…As the increased risk of CVD coincides with menopause, studies have shown that female hormones, especially estrogens, are cardioprotective and play significant roles in both reproductive and non-reproductive systems [ 2 ]. Menopause is associated with a significant increase of blood pressure, body mass index (BMI), obesity, and body fat distribution [ 3 ]. Moreover, they can be synthesized in non-reproductive tissues such as the bone, brain, liver, heart, and muscles [ 4 ].…”