The Outcomes of Infants with HIV Infected Mother in a Tertiary Hospital in Indonesia

Abstract

Background: Infant from HIV mother face the risk of HIV infection. Effective prevention on mother-tochild transmission (PMTCT) program increasing the number of uninfected infants in East Java Indonesia. This study describes the outcomes of infants with HIV mother in Dr. Soetomo Hospital, a tertiary referral hospital in East Java, related to outcome (infectious morbidity, nutritional status, immunodeficiency status, growth/development, and incidence of anemia). Method:This cross-sectional study analyzed 0-18 months infant and HIV mother pairs at HIV outpatient clinic Dr. Soetomo General Hospital from January to April 2017. The data were collected and analyzed using Fisher's exact test and chi-square test with P<0.05.Results: Fourty HIV-infected mothers and infants pairs were analyzed, separated into two groups positive (3 infants) and negative (37 infants) Anti HIV PCR. There were 19 male. Age distribution (6 weeks-5 months 40%; 6-11 months 47.5%; 12-18 months 12.5%). Five percent were born prematurely, 77.5% infant has normal birth-weight. Only 2.5% were fed breast milk, AZT-cotrimoxazole were given to 87.5% infant while the rest received AZT/3TC/NVP. Immunizations of the infants were mostly (60%) up to date. Infectious morbidity (P=0.433), WAZ-score (P=0.666), LAZ-score (P=0,973), WLZ-score (P=0.219) and incidence of anemia (P=0.548) were not significant differences between groups. The development test using DDST II (P=0,001), as well as immunodeficiency status [presence of immunodeficiency (P<0.001)] was significantly different between groups. conclusion: There were significant effects of HIV exposed on the development and immunodeficiency status in 0-18 months infant.

Diagnostic test of Brief Peripheral Neuropathy Screen as Distal Sensory Polyneuropathy-HIV Diagnostic Tool

“…Human immunodeficiency virus (HIV) is a retrovirus that can cause immune system failure in humans 1,2 . It is estimated that 35.…”