The Outcomes of Patients Incidentally Confirmed with Covid-19 After Cardiac Surgery

Uysal, Ayhan; Ertürk, Esra; Abacilar, Ahmet Feyzi; Duman, Umit; Dogan, Omer Faruk

doi:10.1532/hsf.4259

Cited by 4 publications

(4 citation statements)

References 13 publications

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“…Finally, in this pandemic era, several viral postoperative cases of pneumonia have been ascribed to COVID-19 in patients that resulted RT-PCR test negative before cardiac surgery; immunologic disorders by the use of extracorporeal circulation, physiologic distress, and anesthesia would be responsible for COVID-19 activation during the incubation period [ 41 ].…”

Section: Risk Factorsmentioning

confidence: 99%

Nosocomial Extracardiac Infections After Cardiac Surgery

Zardi

Chello

Zardi³

et al. 2022

Curr Infect Dis Rep

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Purpose of Review Nosocomial extracardiac infections after cardiac surgery are a major public health issue affecting 3–8.2% of patients within 30–60 days following the intervention. Recent Findings Here, we have considered the most important postoperative infective complications that, in order of frequency, are pneumonia, surgical site infection, urinary tract infection, and bloodstream infection. The overall picture that emerges shows that they cause a greater perioperative morbidity and mortality with a longer hospitalization time and excess costs. Preventive interventions and corrective measures, diminishing the burden of nosocomial extracardiac infections, may reduce the global costs. A multidisciplinary team may assure a more appropriate management of nosocomial extracardiac infections leading to a reduction of hospitalization time and mortality rate. Summary The main and most current data on epidemiology, prevention, microbiology, diagnosis, and management for each one of the most important postoperative infective complications are reported. The establishment of an antimicrobial stewardship in each hospital seems to be, at the moment, the more valid strategy to counteract the challenging problems.

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Section: Risk Factorsmentioning

confidence: 99%

Nosocomial Extracardiac Infections After Cardiac Surgery

Zardi

Chello

Zardi³

et al. 2022

Curr Infect Dis Rep

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“…In that same study, fatal outcomes were associated with decreased levels of serum albumin, and an open surgical procedure, the oxygen desaturation at the time of the COVID-19 diagnosis, and a PCR cycle threshold (Ct) value <20 were related to mortality (14). Furthermore, in their study on patients who underwent cardiac surgery and were then incidentally detected with COVID-19 post-surgery, Uysal et al (15) Table II reported a mortality rate of 20.7%, while in that same study, increased neutrophil and decreased lympocyte counts were associated with poor outcomes. Tabourin et al (16), in a post-operative assessment of the nosocomial transmission of COVID-19 following robotic surgery for urinary and gynecological cancer, as well as Bacalbasa et al (17) in a post-operative assessment of the nosocomial transmission of COVID-19 following surgery for ovarian cancer, found low mortality rates.…”

Section: Discussionmentioning

confidence: 95%

Biomarkers predicting the 30‑day mortality of patients who underwent elective surgery and were infected with SARS‑CoV‑2 during the post‑operative period: A retrospective study

et al. 2022

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The coronavirus disease 2019 (COVID-19) pandemic is a significant global concern that has had major implications for the healthcare system. Patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) undergoing elective or emergency surgical procedures have a substantial risk of mortality and peri-operative complications. The present study aimed to describe the characteristics of patients who underwent elective surgery and developed nosocomial SARS-CoV-2 infection post-surgery. Patients who underwent thoracic, upper and lower abdominal or peripheral elective surgery with a polymerase chain reaction diagnosis of COVID-19, at 3-7 days after the surgery, were enrolled in the present retrospective study. Demographics, vaccination status against SARS-CoV-2, Charlson comorbidity index (CCI) and laboratory data were recorded upon admission to the hospital unit. In total, 116 subjects (80 males, 36 females; mean age, 67.31±16.83 years) fulfilling the inclusion criteria were identified. Among the 116 participants, 14 (12.1%) were intubated. From the 116 individuals analyzed, 84 were alive after 30 days (survivors), and 32 had succumbed to the disease (non-survivors). The mortality rate was 27.6% (32/116). The non-survivors had an older age and a higher CCI score. At the evaluation upon admission to the hospital unit, the survivors presented with higher serum albumin levels and a higher number of blood lymphocytes. In addition, the survivors exhibited lower levels of lactate dehydrogenase, aspartate aminotransferase, alkaline phosphatase (ALP) and C-reactive protein (CRP), as well as a higher neutrophil to lymphocyte ratio (NLR) and CRP to albumin ratio (CAR) (P<0.05). The patients that were intubated had higher levels of gamma glutamyl-transferase (GGT), ALP and ferritin, as well as a higher NLR and platelet to lymphocyte ratio upon admission to the hospital unit (P<0.05). According to the Cox proportional hazards multivariate regression analysis, the only independent predictors of mortality and intubation were ALP and GGT upon admission, respectively (P<0.05). On the whole, the findings of the present study suggest that more stringent guidelines are required in order to prevent infection during the post-operative period.

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“…In a multi-center study consisting of 826 patients, the incidence of postoperative COVID-19 was reported as 5.8% after cardiac surgery. [ 1 ]…”

Section: Introductionmentioning

confidence: 99%

“…In a multi-center study consisting of 826 patients, the incidence of postoperative COVID-19 was reported as 5.8% after cardiac surgery. [1] The number of studies on the outcomes of COVID-19 occurring in the recovery period of open-heart surgery is very limited. [2] In the present study, we aimed to examine the effect of COVID-19 on the healing process of patients undergoing open-heart surgery.…”

mentioning

confidence: 99%