The Outcomes of Robotic Rehabilitation Assisted Devices Following Spinal Cord Injury and the Prevention of Secondary Associated Complications

Nistor-Cseppentö, Delia Carmen; Gherle, Anamaria; Negruț, Nicoleta; Bungău, Simona; Sabau, Anca Maria; Radu, Andrei-Flavius; Bungău, Alexa Florina; Ţiţ, Delia Mirela; Uivaraseanu, Bogdan; Ghitea, Timea Claudia; Uivaroșan, Diana

doi:10.3390/medicina58101447

Cited by 16 publications

(9 citation statements)

References 90 publications

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“…The current study reveals a lack of statistically significant correlation between BMI and sex, aligning with numerous similar studies conducted by peers (15,16). In certain studies investigating muscle or bone mass loss, a parallel relationship between age and BMI can be observed (17,18). In this particular study, the correlation between age and BMI was not found to be statistically significant.…”

Section: Discussionsupporting

confidence: 78%

Assessing the Risk of Stroke in the Elderly in the Context of Long-COVID, Followed Through the Lens of Family Medicine

MOLDOVAN,

MOGA,

MOGA

et al. 2023

In Vivo

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Background/Aim: Patients infected with COVID-19 may experience a range of acute and chronic neurological disorders. While severe neurological complications like strokes and seizures were less common during the acute or post-COVID period, the long-term effects of COVID-19, known as long COVID, have received limited attention. This study aimed to examine the lasting consequences of SARS-CoV-2 infection and establish potential connections with related diseases. Patients and Methods: We followed a group of 157 patients for one year, predominantly from urban areas (61.8%), divided into three groups based on the presence of associated diseases that pose health risks: the control (43 patients), low-risk (67 patients), and high-risk (47 patients) groups. Results: We observed an inverse relationship between oxygen saturation and erythrocyte sedimentation rate, as well as a direct relationship between varicose disease and dyslipidemia, and gastrointestinal disease. Additionally, we noticed a less significant improvement in oxygen saturation and increased prevalence of psychoanxiety disorders in individuals undergoing anticoagulant treatment. Conclusion: The impact of long COVID and its secondary effects, which persist for an extended period and are influenced by associated diseases, can be effectively monitored and addressed by primary care physicians. These findings can serve as a basis for developing more efficient approaches to managing the long-term consequences of COVID-19.COVID-19 patients have the potential to develop various acute neurological disorders, such as loss of taste and smell (ageusia and anosmia), abnormal brain wave patterns (epileptiform abnormalities), brain inflammation (encephalopathy), stroke (cerebral infarction), nerve damage in the extremities (peripheral neuropathy), and muscle inflammation (myositis). The long-term neurological conditions associated with COVID-19 are not yet clearly defined, but commonly reported syndromes include dysautonomia (problems with the autonomic nervous system), neurocognitive dysfunction, different types of pain syndromes, persistent fatigue, and reduced tolerance for physical exertion (1).A retrospective observational case series conducted in Wuhan revealed that a significant proportion (36.4%) of 214 hospitalized patients with SARS-CoV-2 infection exhibited some form of neurological involvement. This indicates that neurological manifestations may be overlooked and not adequately reported in the progression of the disease. Among patients with central nervous system (CNS) involvement, the most frequently reported symptoms were headache (13%) and dizziness (17%). However, more severe neurological complications, such as strokes and seizures, were less prevalent, occurring in only 3% and 0.5% of cases, respectively (2).Antiphospholipid syndrome (APS) is distinguished from other coagulation disorders by its prominent occurrence of arterial thromboses. The most frequently observed arterial thromboses in APS affect the intracranial arteries, resulting in strokes and trans...

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Section: Discussionsupporting

confidence: 78%

Assessing the Risk of Stroke in the Elderly in the Context of Long-COVID, Followed Through the Lens of Family Medicine

MOLDOVAN,

MOGA,

MOGA

et al. 2023

In Vivo

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“…Current treatment for PD is mainly symptomatic, including levodopa, dopamine agonists, catechol-O-methyltransferase inhibitors and monoamine oxidase B inhibitors. Nevertheless, these medicines are focused on PD manifestations rather than limiting disease progression [ 50 ]. Likewise, other groups of drugs, such as the AchEIs, memantine and atypical antipsychotics, are focused on treating non-motor symptoms, such as apathy, depression and autonomic dysfunction.…”

Section: Indp In Chronic Neurodegenerative Diseasesmentioning

confidence: 99%

Immunization with Neural-Derived Peptides in Neurodegenerative Diseases: A Narrative Review

et al. 2023

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Neurodegenerative diseases (NDDs) are a major health problem worldwide. Statistics suggest that in America in 2030 there will be more than 12 million people suffering from a neurodegenerative pathology. Furthermore, the increase in life expectancy enhances the importance of finding new and better therapies for these pathologies. NDDs could be classified into chronic or acute, depending on the time required for the development of clinical symptoms and brain degeneration. Nevertheless, both chronic and acute stages share a common immune and inflammatory pathway in their pathophysiology. Immunization with neural-derived peptides (INDP) is a novel therapy that has been studied during the last decade. By inoculating neural-derived peptides obtained from the central nervous system (CNS), this therapy aims to boost protective autoimmunity, an autoreactive response that leads to a protective phenotype that produces a healing environment and neuroregeneration instead of causing damage. INDP has shown promising findings in studies performed either in vitro, in vivo or even in some pre-clinical trials of different NDDs, standing as a potentially beneficial therapy. In this review, we will describe some of the studies in which the effect of INDP strategies have been explored in different (chronic and acute) neurodegenerative diseases.

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“…The impact of robotics resonates beyond the confines of the operating room, extending to the rehabilitation phase. Robotics-assisted rehabilitation devices, including exoskeletons and motion-capture systems, are revolutionizing how patients regain mobility and strength after orthopedic procedures [ 6 ]. These devices provide targeted exercises, monitor progress, and adjust the rehabilitation regimen based on real-time data, thus ensuring optimal recovery trajectories.…”

Section: Editorialmentioning

confidence: 99%

Revolutionizing Orthopedic Healthcare: The Role of Robotics

Ram,

Jeyaraman,

Jeyaraman

et al. 2023

Cureus

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Integrating robotics into orthopedic healthcare represents a transformative paradigm shift driven by technological advancements. This editorial explores the profound impact of robotics on the diagnosis, treatment, and rehabilitation of musculoskeletal conditions. Robotics redefines precision in orthopedic surgery through advanced imaging and real-time feedback, resulting in minimized disruption to tissues and faster recovery. Personalized treatment plans leverage robotics' capabilities to tailor procedures to individual anatomical characteristics, enhancing outcomes and reducing complications. Minimally invasive procedures, facilitated by robotics, mitigate trauma and expedite patient recovery. This collaboration between surgeons and robotic systems enhances precision without supplanting human expertise. Moreover, robotics extends to postoperative rehabilitation, utilizing exoskeletons and motion-capture systems to optimize mobility and strength recovery. While challenges of cost and training exist, proactive collaborations are shaping the future of robotics in orthopedic care. Ethical considerations underline the importance of balancing human intervention with robotic assistance. As robotics evolves, orthopedic healthcare embraces a future where technology and human expertise synergize, ultimately conquering musculoskeletal conditions.

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The Outcomes of Robotic Rehabilitation Assisted Devices Following Spinal Cord Injury and the Prevention of Secondary Associated Complications

Cited by 16 publications

References 90 publications

Assessing the Risk of Stroke in the Elderly in the Context of Long-COVID, Followed Through the Lens of Family Medicine

Assessing the Risk of Stroke in the Elderly in the Context of Long-COVID, Followed Through the Lens of Family Medicine

Immunization with Neural-Derived Peptides in Neurodegenerative Diseases: A Narrative Review

Revolutionizing Orthopedic Healthcare: The Role of Robotics

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