The Oxygen Consumption of the Human Kidney During Heavy Tubular Excretory Work

History of Dietary Protein Therapy for the Treatment of Chronic Renal Disease from the Mid 1800s until the 1950s

“…First, as previously discussed, urea feeding did not appear to damage the kidney [17]. Second, renal oxygen consumption did not increase during osmotic diuresis [32,33]. Most of the energy expenditure of the kidney is due to the renal tubular reabsorption of solutes, and particularly sodium and chloride [34] and is not associated with the excretion of osmolytes or concentration of the urine by the kidney.…”

Exercise and Heart Disease

“…The oxygen uptake of the kidneys has been shown to remain constant during extreme renal metabolic activity (Bucht et al, 1949;Clark and Barker, 1949), and there is little doubt that changes in A-V difference are a direct reflection of changes in blood flow. The tip of the catheter was passed well into the right renal vein and its position checked again by radioscopy after exercise.…”