The Passerini three-component reaction of aldehyde end-functionalized polymers via RAFT polymerization using chain transfer agents featuring aldehyde

Acrolein-free synthesis of polyacrolein derivatives via the chemo-selective reduction of polyacrylates

“…23,24 For this, poly(mPEGA-co-acrolein) was subjected to Passerini three component reaction (Passerini-3CR) in CHCl 3 in the presence of excess amounts of isocyanide and carboxylic acid. 25,26 Specically, we selected 2-thiophenecarboxylic acid and 1,1,3,3-tetramethyl butyl isocyanide as model reactants and set the following reaction conditions: 50 °C temperature, 8 h reaction time. According to the NMR result depicted in Fig.…”

Recent Advances in Separation-Based Techniques for Synthetic Polymer Characterization

“…In more recent publications, APC technology has been demonstrated as an efficient tool for rapid and highly informative characterization of synthetic hydrocarbon aviation lubricating oils (SHALOs), polystyrenes bearing aldehyde chain end functionality, technical lignins, depolymerization products of lignosulfonates and starches …”

“…In more recent publications, APC technology has been demonstrated as an efficient tool for rapid and highly informative characterization of synthetic hydrocarbon aviation lubricating oils (SHALOs), 21 polystyrenes bearing aldehyde chain end functionality, 22 technical lignins, 23 depolymerization products of lignosulfonates 24 and starches. 25 An APC technique for rapid determination of molecular weight and distribution of acid catalyzed depolymerization products of lignosulfonate at different temperatures (70, 100, and 130 °C) was reported.…”

Genome engineering allows selective conversions of terephthalaldehyde to multiple valorized products in bacterial cells

“…Interestingly, we discovered that we could use the RARE.Δ6 strain to stably accumulate the monoaldehyde mono-alcohol 4-(hydroxymethyl) benzaldehyde (4HMB), which can be used in polymer applications as a precursor that is converted to an aryl bromide on route to polymers bearing an aldehyde at their chain ends 38 . To determine if we could overcome reduction of either aldehyde functional group by identifying and inactivating additional aldehyde reductases, we used multiplex automatable genome engineering (MAGE) to perform translational gene inactivation of up to 10 additional ADH and AKR genes, partly guided by RNA-seq that revealed a previously unreported target whose expression was elevated by TPAL challenge.…”