The Pathogenesis and Aetiology of MIH: More Questions Than Answers

Manton, David J.; Crombie, Felicity; Silva, Mihiri

doi:10.1007/978-3-030-31601-3_4

Cited by 5 publications

(3 citation statements)

References 57 publications

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“…Regarding the etiology of MIH, researchers have not yet reached a clear consensus. Most of the factors that have been implicated so far include childhood illnesses, medications taken during amelogenesis (such as antibiotics), environmental toxins, fever, asthma, and pneumonia [13,15,16].…”

Section: Etiologymentioning

confidence: 99%

Minimally Invasive Therapy for Treating White Spot Lesions on Anterior Teeth in Molar Incisor Hypo Mineralization

Hajer

2023

J Clin Med Surgery

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Section: Etiologymentioning

confidence: 99%

Minimally Invasive Therapy for Treating White Spot Lesions on Anterior Teeth in Molar Incisor Hypo Mineralization

Hajer

2023

J Clin Med Surgery

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“…Molar Incisor Hypomineralization (MIH) is an anomaly that mainly affects the first permanent molars, and can also affect the permanent incisors (FRASCINO et al, 2017;DHAREULA et al, 2018). Clinically, IMH presents with abnormal translucency and opacity in tooth enamel, and may exhibit superficial or deep cavities, vertical or horizontal grooves, and partial or total absence of tooth enamel (MANTON et al, 2020;SILVA-JUNIOR et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Molar-incisor hypomineralization in pediatric dentistry: a literature review

Corrêa,

Uchôa,

Corrêa

et al. 2024

Health of Tomorrow: Innovations and Academic Research

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Hypomineralization is a failure in tooth enamel due to interference with the calcification process. One of the manifestations of this anomaly is Incisor Molar Hypomineralization (MIH), which mainly affects molars and, occasionally, permanent incisors. In this review of HMI in pediatric dentistry, we explore everything from diagnosis to treatment options. The etiology of HMI is idiopathic and multifactorial, often confused with other dental conditions due to similar clinical features. Difficulty in establishing an accurate diagnosis can hinder the treatment plan. Challenges such as hypersensitivity, fear and anxiety of the child, as well as adherence to restorative materials, are faced in the clinical practice of the dental surgeon. Difficulty brushing and the presence of pain in children with HMI negatively impact quality of life. Treatment is complex, adapted to the severity of the affected teeth, ranging from preventive measures to restorative procedures and extractions. The study of HMI is crucial for pediatric dentists, allowing for accurate diagnoses and appropriate treatments, contributing to improving the quality of life of affected patients.

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“…Despite numerous studies to determine the etiological/ causative factors of MIH, apart from a general consensus that it is associated with childhood illness and genetic susceptibility, the causative factor(s) is(are) yet to be determined. 11 Clinically, in terms of location and boundaries, lesions are located in the middle and incisal/occlusal third of teeth and show a sharp demarcation between affected and sound enamel; lesions vary greatly in terms of size and shape, with a wide variation in color. 12 Anterior lesions can affect the appearance and perception of the affected teeth and 'smile', and may affect the quality of life, and improvement in appearance can improve both self and others' perception.…”

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confidence: 99%

The use of transillumination in mapping demarcated enamel opacities in anterior teeth: A cross‐sectional study

Marouane¹,

Manton

2021

Int J Paed Dentistry

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Molar incisor hypomineralization (MIH) is a qualitative developmental defect of enamel affecting a minimum of one first permanent molar, often with involvement of the permanent incisors. 1 Despite MIH having been detected among ancient populations, 2,3 it was first identified in 1987 by Koch and defined in 2001. 1,4 MIH lesions differ considerably from sound enamel. Microscopically, these lesions present disorganized enamel prisms and large inter-prismatic spaces occupied by a protein-rich matrix associated with decreased mineral density, hardness, and fracture resistance. This explains the increased surface porosity and post-eruptive breakdown (PEB) of the enamel surface (especially in severe lesions) and the greater susceptibility to dental caries; and also why affected teeth are often hypersensitive. [5][6][7][8][9][10]

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The Pathogenesis and Aetiology of MIH: More Questions Than Answers

Cited by 5 publications

References 57 publications

Minimally Invasive Therapy for Treating White Spot Lesions on Anterior Teeth in Molar Incisor Hypo Mineralization

Minimally Invasive Therapy for Treating White Spot Lesions on Anterior Teeth in Molar Incisor Hypo Mineralization

Molar-incisor hypomineralization in pediatric dentistry: a literature review

The use of transillumination in mapping demarcated enamel opacities in anterior teeth: A cross‐sectional study

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