The pathogenesis of Munchausen syndrome a review and case report

Babe, Kenneth S.; Peterson, Anita M.; Loosen, Peter T.; Geracioti, Thomas D.

doi:10.1016/0163-8343(92)90098-u

Cited by 20 publications

(6 citation statements)

References 11 publications

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“…Specifically, although lying in cognitive studies of deception is often artificial and experimental, pathological lying is based on actual (not experimental) behaviors observed in real-life situations, providing a valuable piece of evidence for the neurobiology of deception. Careful scrutiny of the literature has revealed case reports that shed light on several forms of pathological lying and their possible neurological correlates (Aouille and others 2003; Babe and others 1992; Diefenbacher and Heim 1997; Fenelon and others 1991; Modell and others 1992; Mountz and others 1996; for review, see Abe 2009). However, the findings are extremely diverse, and interpretation of the data remains difficult because of the ungeneralizability inherent in case studies.…”

Section: Pathological Lying and The Underlying Neural Mechanisms: A Pmentioning

confidence: 99%

How the Brain Shapes Deception

Abe

2011

Neuroscientist

116

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How do people tell a lie? One useful approach to addressing this question is to elucidate the neural substrates for deception. Recent conceptual and technical advances in functional neuroimaging have enabled exploration of the psychology of deception more precisely in terms of the specific neuroanatomical mechanisms involved. A growing body of evidence suggests that the prefrontal cortex plays a key role in deception, and some researchers have recently emphasized the importance of other brain regions, such as those responsible for emotion and reward. However, it is still unclear how these regions play a role in making effective decisions to tell a lie. To provide a framework for considering this issue, the present article reviews current accomplishments in the study of the neural basis of deception. First, evolutionary and developmental perspectives are provided to better understand how and when people can make use of deception. The ensuing section introduces several findings on pathological lying and its neural correlate. Next, recent findings in the cognitive neuroscience of deception based on functional neuroimaging and loss-of-function studies are summarized, and possible neural mechanisms underlying deception are proposed. Finally, the priority areas of future neuroscience research-human honesty and dishonesty-are discussed.

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Section: Pathological Lying and The Underlying Neural Mechanisms: A Pmentioning

confidence: 99%

How the Brain Shapes Deception

Abe

2011

Neuroscientist

116

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“…3,4 Existem algumas teorias sobre a patogênese da SM, como a de Pankratz & Lezak, que descreve uma disfunção no hemisfé-rio direito em pacientes com Munchausen; de King & Ford, que relata anormalidades no sistema nervoso central em 40% dos 72 pacientes estudados (focos epileptogênicos, lesões cranianas de diversas etiologias, infecções prévias, anormalidades no EEG); e de Evans et al, que fala de alteração no sistema hipotalâmico-pituitário-adrenal. [5][6][7][8][9] História de trauma psicoló-gico pode existir, como privações na infância, abuso infantil, …”

Section: Discussionunclassified

“…Normalmente existe alguma experiência ou contato com a área de saúde e traços de personalidade anti-social. 8,9,10 O paciente tem passagens por vários hospitais, sendo na maioria deles novamente investigado. Também é descrito que essas passagens por instituições podem ser apenas mais um componente fantasioso da doença.…”

Section: Síndrome De Munchausenunclassified

Síndrome de Munchausen: relato de caso e revisão da literatura

Menezes

Holanda

Silveira

et al. 2002

Rev. Bras. Psiquiatr.

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Descrita pela primeira vez pelo médico inglês Richard Asher, em 1951, a síndrome de Munchausen (SM) é um transtorno factício em que o paciente se mostra aguda e dramaticamente doente, com a habilidade de mimetizar sinais e sintomas de forma a necessitar de internações prolongadas, procedimentos de diagnósticos invasivos, longo tempo de terapia com as mais variadas classes de drogas e cirurgias. Descreve-se um caso de SM do Hospital Universitário Walter Cantídio, da Universidade Federal do Ceará, em que a paciente apresentava artrite e enfisema subcutâneo. Na ocasião, ela tinha 26 anos, era agente de saúde e tinha sérios problemas familiares. Este estudo também aborda uma revisão de literatura.

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“…Psychological factors, such as longing for nurturance, feelings of helplessness, desire to feel superior, and anger toward physicians, have been emphasized by authors. [15][16][17][18] More recently, articles have emphasized underlying brain dysfunction in 20% to 25% of patients with Munchausen syndrome. 19 Abnormalities have been reported in brain images 15,20 and neuropsychological testing.…”

Section: Etiology and Epidemiologymentioning

confidence: 99%

“…[15][16][17][18] More recently, articles have emphasized underlying brain dysfunction in 20% to 25% of patients with Munchausen syndrome. 19 Abnormalities have been reported in brain images 15,20 and neuropsychological testing. Accurate epidemiologic data are unavailable because deception is an integral part of factitious disorders.…”

Section: Etiology and Epidemiologymentioning

confidence: 99%