2015
DOI: 10.3109/02713683.2015.1017650
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The Pathogenesis of Raised Intraocular Pressure in Uveitis

Abstract: Uveitic glaucoma is caused by a number of different diseases, some of which present with acute hypotony, others with acutely raised IOP, and others which demonstrate an increase in IOP over time. Further studies should be carried out to examine the differing pathogenesis in these types of diseases, and to establish the best treatment options.

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Cited by 48 publications
(40 citation statements)
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“…In the case of uveitis, a form of glaucoma called inflammatory, or uveitic, glaucoma can result from obstruction of drainage structures in the anterior segment as a secondary consequence of the ocular inflammation (Bodh et al , 2011; Siddique et al , 2013; Baneke et al , 2015). In the case of steroid-induced glaucoma, the steroids are generally thought to be deleterious, not by their action in reducing inflammation, but rather by acting directly to affect the drainage structures, among other things, by increasing extracellular matrix deposition by trabecular meshwork cells, which increases outflow resistance and consequently increased intraocular pressure (Clark et al , 1995; Tektas et al , 2011; Overby et al , 2014; Raghunathan et al , 2015; Taurone et al , 2015).…”
Section: Neuroinflammation In Glaucomamentioning
confidence: 99%
“…In the case of uveitis, a form of glaucoma called inflammatory, or uveitic, glaucoma can result from obstruction of drainage structures in the anterior segment as a secondary consequence of the ocular inflammation (Bodh et al , 2011; Siddique et al , 2013; Baneke et al , 2015). In the case of steroid-induced glaucoma, the steroids are generally thought to be deleterious, not by their action in reducing inflammation, but rather by acting directly to affect the drainage structures, among other things, by increasing extracellular matrix deposition by trabecular meshwork cells, which increases outflow resistance and consequently increased intraocular pressure (Clark et al , 1995; Tektas et al , 2011; Overby et al , 2014; Raghunathan et al , 2015; Taurone et al , 2015).…”
Section: Neuroinflammation In Glaucomamentioning
confidence: 99%
“…No se asocia a ninguna enfermedad sistémica ni ocular, por lo que se le considera un diagnóstico de exclusión. Dentro de sus complicaciones más frecuentes se encuentra: catarata (40%), neovascularización coroidea (30%), edema macular cistoide (30%) y glaucoma uveítico (10%) [1][2][3][4] . El caso presentado tuvo catarata y glaucoma uveítico como complicaciones, siendo esta última la de más difícil manejo.…”
Section: Discussionunclassified
“…Una de sus peores complicaciones por la dificultad en su manejo terapéutico es el glaucoma uveítico (GU) [1] . El GU fue descrito por primera vez por Joseph Beer en 1813 [1,2] , y se estima que un 20% a 40% de pacientes con uveítis desarrollan GU (6,5% al año, 11,1% a los cinco años y 22,7% a los diez años) [1,3,4] .…”
Section: Introductionunclassified
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