The pathogenetic role of cerebral hyperthermia in brain lesion

Шевелев, О. А.; Бутров, А. В.; Cheboksarov, D. V.; Ходорович, Н. А.; Lapaev, N. N.; Pokatilova, N. S.

doi:10.18821/0023-2149-2017-95-4-302-309

Cited by 10 publications

(2 citation statements)

References 16 publications

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“…The lengthening of the cooling period by up to 4 hours made it possible to reduce the average temperature of the cerebral cortex by 2.5-4 °C. The basal temperature did not change significantly during this duration of cooling, as did blood pressure and heart rate [29].…”

Section: Temperature Balance Of the Brain And Cchmentioning

confidence: 71%

Diagnostics and prevention of sports-related traumatic brain injury complication

Shevelev,

Smolensky,

Petrova

et al. 2023

Vestn. Ross. univ. družby nar., Ser. Med.

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Sports-related traumatic brain injuries (TBI) accounts for up to 20 % of all injuries that are obtained by athletes and its incidence rises annually due to rise in population involving in sports, growing popularity of extreme sports and high level of motivation to achieve record results among young sportsmen. The aim of the review is to present the potential benefits of using microwave radiothermometry and craniocerebral hypothermia technologies in sports-related TBI. The review considers most common form of traumatic brain injury in athletes - mild TBI, which in turn can provoke a wide range of complications and negative consequences in near and delayed periods after the injury. The main shortcomings of programs for complication prevention in treatment and rehabilitation of athletes after TBI are considered, which do not take into account the peculiarities of injury mechanisms, its significant differences from household, road or criminal injuries with brain damage. Lack of objective methods of instrumental diagnosis for injury severity is also described. In addition, pathophysiological component characteristics of sports TBI is accentuated: frequency of repetition, increasement of brain and body temperature, peripheral redistribution of blood flow and hypocapnia, which significantly affects cerebral blood flow. Based on the analysis of the available scientific literature, it is elicited that TBI is an independent cause of cerebral hyperthermia development, which significantly aggravates the consequences of the injury. Conclusions. The authors propose an innovative way to use microwave radiothermometry method as a diagnostic tool for sports-related TBI. In addition, the review highlights the main recommendations for complications prevention by using craniocerebral hypothermia technology, which reduces overall physical and cerebral hyperthermia, and augments the resistance of cerebral cortex neurons to hypoxia and trauma. However, the authors believe that the described approaches in sports medicine are not used purposefully due to lack of awareness of sports team doctors and coaches.

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Section: Temperature Balance Of the Brain And Cchmentioning

confidence: 71%

Diagnostics and prevention of sports-related traumatic brain injury complication

Shevelev,

Smolensky,

Petrova

et al. 2023

Vestn. Ross. univ. družby nar., Ser. Med.

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show abstract

“…Neurogenic fever and cerebral hyperthermia are not only the markers of acutely developing brain lesions, but also an important link in pathogenesis that worsens the course and outcomes of the disease, which can be stopped by using temperature-lowering technologies [ 18 ].…”

Section: Correction Of Brain Temperature Balance Disruption In Patien...mentioning

confidence: 99%

Correction of Local Brain Temperature after Severe Brain Injury Using Hypothermia and Medical Microwave Radiometry (MWR) as Companion Diagnostics

et al. 2023

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The temperature of the brain can reflect the activity of its different regions, allowing us to evaluate the connections between them. A study involving 111 patients in a vegetative state or minimally conscious state used microwave radiometry to measure their cortical temperature. The patients were divided into a main group receiving a 10-day selective craniocerebral hypothermia (SCCH) procedure, and a control group receiving basic therapy and rehabilitation. The main group showed a significant improvement in consciousness level as measured by CRS-R assessment on day 14 compared to the control group. Temperature heterogeneity increased in patients who received SCCH, while remaining stable in the control group. The use of microwave radiometry to assess rehabilitation effectiveness and the inclusion of SCCH in rehabilitation programs appears to be a promising approach.

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Thermal Balance of the Brain and Markers of Inflammatory Response in Patients with Schizophrenia

et al. 2022

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The pathogenetic role of cerebral hyperthermia in brain lesion

Cited by 10 publications

References 16 publications

Diagnostics and prevention of sports-related traumatic brain injury complication

Diagnostics and prevention of sports-related traumatic brain injury complication

Correction of Local Brain Temperature after Severe Brain Injury Using Hypothermia and Medical Microwave Radiometry (MWR) as Companion Diagnostics

Thermal Balance of the Brain and Markers of Inflammatory Response in Patients with Schizophrenia

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