The pathophysiological effect of scarlet fever toxin

The role played by lymphocytes in the pyretic response to scarlet fever toxin (ET) was studied in vivo using antilymphocyte serum (ALS). Two i.v. injections of ALS inhibited the pyretic response to a subsequent ET injection in rabbits. The course of endotoxin fever remained uninfluenced by ALS. Antipolymorphonuclear serum had no effect on the pyretic response to either of the toxins. Pretreatment with ALS also inhibited the skin reaction after i.d. injection of ET. These findings are further evidence a mediating role of lymphocytes in the biological effects of ET, among other things in the release of endogenous pyrogen.

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Influence of antilymphocyte and antipolymorphonuclear sera on the pyrogenic effect of scarlet fever toxin

Hřı́balová

Castrová²,

Pekárek³

1979

Folia Microbiol

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Purification and characterization of erythrogenic toxins II. communication: In vivo biological activities of erythrogenic toxin produced by streptococcus pyogenes strain NY-5

Hřı́balová

Knöll²,

Gerlach³

1980

Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. 1. A

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The pathophysiological effect of scarlet fever toxin

Cited by 2 publications

References 28 publications

Influence of antilymphocyte and antipolymorphonuclear sera on the pyrogenic effect of scarlet fever toxin

Influence of antilymphocyte and antipolymorphonuclear sera on the pyrogenic effect of scarlet fever toxin

Purification and characterization of erythrogenic toxins II. communication: In vivo biological activities of erythrogenic toxin produced by streptococcus pyogenes strain NY-5

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