2015
DOI: 10.1371/journal.pone.0127316
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The Patient- And Nutrition-Derived Outcome Risk Assessment Score (PANDORA): Development of a Simple Predictive Risk Score for 30-Day In-Hospital Mortality Based on Demographics, Clinical Observation, and Nutrition

Abstract: ObjectiveTo develop a simple scoring system to predict 30 day in-hospital mortality of in-patients excluding those from intensive care units based on easily obtainable demographic, disease and nutrition related patient data.MethodsScore development with general estimation equation methodology and model selection by P-value thresholding based on a cross-sectional sample of 52 risk indicators with 123 item classes collected with questionnaires and stored in an multilingual online database.SettingWorldwide prospe… Show more

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Cited by 34 publications
(31 citation statements)
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References 36 publications
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“…The clinical relevance has been highlighted by the prevalence of malnutrition in hospitals (up to 50% of patients) (4) and the association between inadequate feeding, increased mortality (up to 8 times), and prolonged length of stay (5,6). Although proper diet, both qualitatively and quantitatively, is relevant for a patient's recovery (7,8), the prevalence of reduced meal intake ranges between 50% and 60% (5,(8)(9)(10), and inadequate food intake is rarely followed by nutritional care interventions (10). Furthermore, hospitals produce enormous amounts of food waste, which is an ethical and economic issue.…”
Section: Introductionmentioning
confidence: 99%
“…The clinical relevance has been highlighted by the prevalence of malnutrition in hospitals (up to 50% of patients) (4) and the association between inadequate feeding, increased mortality (up to 8 times), and prolonged length of stay (5,6). Although proper diet, both qualitatively and quantitatively, is relevant for a patient's recovery (7,8), the prevalence of reduced meal intake ranges between 50% and 60% (5,(8)(9)(10), and inadequate food intake is rarely followed by nutritional care interventions (10). Furthermore, hospitals produce enormous amounts of food waste, which is an ethical and economic issue.…”
Section: Introductionmentioning
confidence: 99%
“…The original PANDORA score had a high performance in predicting mortality in hospitalized patients having three main facilitator points: it is based on data available at any time of hospitalization; it is not necessary to spend much additional time collecting data, since the items are part of the patient’s history; and the model is public, international and independent of national codification conventions [2].…”
Section: Discussionmentioning
confidence: 99%
“…It affects almost 50% of adult patients in Latin American countries, including Brazil. About 40% of in-patients are affected by this condition, which represents an independent risk factor for mortality, besides favoring complications during hospitalization [1,2]. The influence of nutritional status on patient prognosis has been reported in the literature some time ago.…”
Section: Introductionmentioning
confidence: 99%
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“…The Patient‐ And Nutrition‐Derived Outcome Risk Assessment (PANDORA) was recently developed and validated in a large, multinational cohort of hospitalized patients . It is a relatively simple tool for predicting 30‐day mortality in acutely ill patients, and since it is based on many traditional markers of nutrition adequacy, it may also be useful to stratify nutrition risk levels; however, its utility in the ICU setting is not known.…”
Section: Introductionmentioning
confidence: 99%