The pattern electroretinogram in glaucoma and ocular hypertension.

Abstract

Thirty one eyes with established glaucoma, 61 high risk ocular hypertensive (OHTs) eyes, 66 medium risk OHT eyes, 58 low risk OHT eyes, and 47 control eyes have been followed for up to 2 years by clinical examination and pattern electroretinography (PERG). The study was

Electroretinographic Abnormalities in a Rat Glaucoma Model with Chronic Elevated Intraocular Pressure

“…Studies in human glaucoma subjects have also documented relatively small changes in basic scotopic ERG parameters (Fazio et al, 1986), but more signi®cant alterations in subcomponents of the scotopic ERG, such as oscillatory potentials and in pattern ERG amplitudes (Vaegan et al, 1991). In human glaucoma there are pattern ERG abnormalities (O'Donaghue et al, 1992) and also changes in the photopic ERG, such as a reduced cone-mediated bwave amplitude and prolonged implicit time (Holopigian et al, 1990).…”

Pattern electroretinograms for the detection of neural loss in patients with permanent temporal visual field defect from chiasmal compression

“…For example, although the test has been shown in several studies [15][16][17] to be valuable as an indicator of neural loss in glaucoma, other authors have questioned its usefulness, claiming that results may be normal in patients with glaucomatous damage [13,[18][19][20]. Recently Hood et al [3] studied 15 patients with confirmed visual field (VF) deficits from glaucoma and concluded that PERG can detect early neural loss even before it is noticeable in the VF, but that patients with clear glaucomatous damage can have normal-appearing PERGs.…”

Symptomatic abnormalities of dark adaptation in patients with EFEMP1 retinal dystrophy (Malattia Leventinese/Doyne honeycomb retinal dystrophy)

“…30,31 The pattern ERG was recorded in one eye using a previously described protocol. 32,33 All ERG testing conformed to International Society for Electrophysiology of Vision (ISCEV) standards. 34,35 Focal ERGs were obtained with a Maculoscope (Diagnosys LLC, Littleton, MA, USA).…”