The Pattern of rpoB gene mutation ofMycobacterium tuberculosisand predictors of rifampicin resistance detected by gene Xpert MTB/Rif in Tanzania
Peter Richard Torokaa,
Heledy Kileo,
Loveness Urio
et al.
Abstract:IntroductionAntimicrobial resistance associated withMycobacterium tuberculosis (MTB)is the challenge facing Tuberculosis (TB) management worldwide. Rifampicin resistance (RR) has been associated with the rpoB gene mutation. No study was conducted in Tanzania to determine the commonest mutation. The inconsistent findings from various studies support the need to determine whether reported mutation patterns are applicable in our setting. We determined the frequency of rpoB gene mutation and factors associated wit… Show more
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