The periodicity between the aggregated microbubbles by secondary radiation force

Harput, Sevan; Raiton, Benjamin; McLaughlan, James R.; Evans, Stephen D.; Freear, Steven

doi:10.1109/ultsym.2011.0405

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…where F 1 drops with increasing driving frequency ω = 2πf . Secondary radiation force originates from the pressure gradients in the re-radiated ultrasonic field from pulsating MBs [13]. The expansion and contraction of a MB generate (Bottom-left) Estimated and measured pressure for two out of phase asymmetric plane waves with apodization.…”

Section: A Acoustic Radiation Forcementioning

confidence: 99%

Simultaneous trapping and imaging of microbubbles at clinically relevant flow rates

Harput

Nie

Cowell

et al. 2016

2016 IEEE International Ultrasonics Symposium (IUS)

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Abstract-Mechanisms for non-invasive target drug delivery using microbubbles and ultrasound have attracted growing interest. Microbubbles can be loaded with a therapeutic payload and tracked via ultrasound imaging to selectively release their payload at ultrasound-targeted locations. In this study, an ultrasonic trapping method is proposed for simultaneously imaging and controlling the location of microbubbles in flow by using acoustic radiation force. Targeted drug delivery methods are expected to benefit from the use of the ultrasonic trap, since trapping will increase the MB concentration at a desired location in human body.The ultrasonic trap was generated by using an ultrasound research system UARP II and a linear array transducer. The trap was designed asymmetrically to produces a weaker radiation force at the inlet of the trap to further facilitate microbubble entrance. A pulse sequence was generated that can switch between a long duration trapping waveform and short duration imaging waveform. High frame rate plane wave imaging was chosen for monitoring trapped microbubbles at 1 kHz. The working principle of the ultrasonic trap was explained and demonstrated in an ultrasound phantom by injecting SonoVue microbubbles flowing at 80 mL/min flow rate in a 3.5 mm diameter vessel.

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Section: A Acoustic Radiation Forcementioning

confidence: 99%

Simultaneous trapping and imaging of microbubbles at clinically relevant flow rates

Harput

Nie

Cowell

et al. 2016

2016 IEEE International Ultrasonics Symposium (IUS)

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Detecting and Characterizing the Fabella with High Frame-Rate Ultrasound Imaging

Berthaume

Toulemonde

Peralta

et al. 2020

2020 IEEE International Ultrasonics Symposium (IUS)

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The fabella is a sesamoid bone usually located in the tendon of the lateral head of the gastrocnemius muscle, behind the knee joint. Prevalence rates in human populations vary widely with an average of 42.5% people having a fabella. Clinically, it is associated with a number of knee ailments, most notably the osteoarthritis of the knee and generalized knee pain (i.e., fabella syndrome). As the function of the fabella remains unknown, the biomechanical consequences of fabella presence/absence can only be speculated. Successfully detecting the fabella, measuring its size and determining its shape, are off importance for clinical and evolutionary researchers. In this work, we compare plane wave imaging with conventional focused imaging and evaluate their performance for detecting and characterizing the fabella.

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The periodicity between the aggregated microbubbles by secondary radiation force

Cited by 2 publications

References 12 publications

Simultaneous trapping and imaging of microbubbles at clinically relevant flow rates

Simultaneous trapping and imaging of microbubbles at clinically relevant flow rates

Detecting and Characterizing the Fabella with High Frame-Rate Ultrasound Imaging

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