The perspective of prostate cancer patients and patients' partners on the psychological burden of androgen deprivation and the dyadic adjustment of prostate cancer couples

Hamilton, Lisa Dawn; Dam, Dexter Van; Wassersug, Richard J.

doi:10.1002/pon.3930

Cited by 24 publications

(15 citation statements)

References 43 publications

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“…Men’s comments about the valued support of their partners is consistent with evidence of the interaction between quality of relationship and men’s mood [ 20 ]; consideration may need to be given to including men’s partners in consultations, if the man agrees. Our results concur with other findings that, in addition to the support of their partners, men value peer support [ 14 , 15 ].…”

Section: Discussionmentioning

confidence: 97%

“…These interviews revealed, too, that the emotional challenges of managing a diagnosis of prostate cancer and its treatment can be difficult not only for men but also for their partners [ 18 , 19 ]. More recently, an online survey found that, when men recovering from prostate cancer and its treatment are in a relationship, there is interaction between the men’s mood and the quality of the relationship [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

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Men’s perceptions of prostate cancer diagnosis and care: insights from qualitative interviews in Victoria, Australia

et al. 2017

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BackgroundThe Victorian Prostate Cancer Registry (Australia) revealed poorer rates of survival for men diagnosed with prostate cancer in one Victorian regional area than for men in metropolitan Melbourne. We sought to explore the perceptions and experiences of prostate cancer diagnosis, treatment, and care of men diagnosed with prostate cancer who lived in regional or metropolitan areas and of men who had not been so diagnosed. Our goal was to contribute to the evidence from which can be built continuing improvements in prostate health care.MethodsUsing the qualitative method of in-depth interviews to gain access to explanation and meaning, we interviewed 21 men: 10 recruited through the Prostate Cancer Outcome Registry-Victoria and 11 from the community. Transcripts were analysed thematically.ResultsWe identified four main themes within which men discussed prostate cancer: Case-finding, Diagnosis, Treatment and Care, and Spreading the Word. Contrasts revealed between regional and metropolitan areas related mostly to the more limited supportive care in regional areas.ConclusionsIt is evident from the perspectives of these men that every aspect of prostate cancer care would benefit from attention: publicising the need to check prostate health, treatment, and supporting men in the years after treatment. Continuing to work on systemic improvements is an important goal for all those committed to men’s health.Electronic supplementary materialThe online version of this article (10.1186/s12885-017-3699-1) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Men’s perceptions of prostate cancer diagnosis and care: insights from qualitative interviews in Victoria, Australia

et al. 2017

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“…Recent studies of sexual bother in men who received ADT for advanced PC indicated that, contrary to expectations, greater sexual bother was associated significantly with greater marital satisfaction (as well as with younger age and shorter duration of ADT) . Those results suggest that couples who are bothered by ADT‐related changes in sexual function and are in accord about the problem can work together to address these changes; and this, in turn, may increase marital satisfaction.…”

Section: Introductionmentioning

confidence: 84%

Psychological effects of androgen‐deprivation therapy on men with prostate cancer and their partners

Donovan

Walker

Wassersug

et al. 2015

Cancer

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111

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The clinical benefits of androgen-deprivation therapy (ADT) for men with prostate cancer (PC) have been well documented and include living free from the symptoms of metastases for longer periods and improved quality of life. However, ADT comes with a host of its own serious side effects. There is considerable evidence of the adverse cardiovascular, metabolic, and musculoskeletal effects of ADT. Far less has been written about the psychological effects of ADT. This review highlights several adverse psychological effects of ADT. The authors provide evidence for the effect of ADT on men's sexual function, their partner, and their sexual relationship. Evidence of increased emotional lability and depressed mood in men who receive ADT is also presented, and the risk of depression in the patient's partner is discussed. The evidence for adverse cognitive effects with ADT is still emerging but suggests that ADT is associated with impairment in multiple cognitive domains. Finally, the available literature is reviewed on interventions to mitigate the psychological effects of ADT. Across the array of adverse effects, physical exercise appears to have the greatest potential to address the psychological effects of ADT both in men who are receiving ADT and in their partners. Cancer 2015;121:4286-99. V C 2015 American Cancer Society.KEYWORDS: androgen-deprivation therapy, cognition, depression, prostate cancer, sexual function. INTRODUCTIONAndrogen-deprivation therapy (ADT) in the form of surgical castration or, more commonly, medical castration is the most common form of treatment for metastatic prostate cancer (PC). [1][2][3] The clinical benefits of ADT for men who have metastatic disease have been well documented and include living free from the symptoms of metastases for longer periods and improved quality of life. 3,4 The use of ADT has increased over time based on clinical trial evidence of improved outcomes. This is especially true for men with high-risk, localized PC who receive radiotherapy and for those with lymph node-positive PC who undergo radical prostatectomy. 1,5,6 In industrialized nations, 50% of men with PC can anticipate being prescribed ADT at some point during the course of their disease. 2 In North America, ADT is currently prescribed for more than 600,000 men with PC. 7 Furthermore, men are being exposed to ADT for periods as long as 5 to 10 years compared with a median duration of 2 to 5 years for patients with metastatic disease. 8 The objective of ADT for men with PC is to reduce levels of androgens-the hormones responsible for stimulating PC cell growth. The principal androgen, testosterone, plays a significant role in male morphology and is the primary determinant of men's sexual behavior, most notably their instinctual sex drive. Testosterone also has been described as a social hormone. 9 Thus, testosterone regulates not only men's desire for sex but also their tendency toward competiveness, dominance, reactive aggression, and stoic emotional presentation. [10][11][12] Descriptive studies of men w...

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“…As noted, the marital relationship between patients with prostate cancer and their spouses has been widely studied in European countries and in the United States (Couper et al., ; Hamilton, Van Dam, & Wassersug, ; Harden et al., ; Manne et al., ; Merz et al., ; Tran et al., ; Wittmann et al., ; Zhou et al., ); such research has rarely been conducted in Asian countries. In this regard, in different cultures, couples have different social role expectations.…”

Section: Introductionmentioning

confidence: 99%

Individual and mutual predictors of marital satisfaction among prostate cancer patients and their spouses

Chien

Chuang

Liu

et al. 2017

Journal of Clinical Nursing

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The perspective of prostate cancer patients and patients' partners on the psychological burden of androgen deprivation and the dyadic adjustment of prostate cancer couples

Cited by 24 publications

References 43 publications

Men’s perceptions of prostate cancer diagnosis and care: insights from qualitative interviews in Victoria, Australia

Men’s perceptions of prostate cancer diagnosis and care: insights from qualitative interviews in Victoria, Australia

Psychological effects of androgen‐deprivation therapy on men with prostate cancer and their partners

Individual and mutual predictors of marital satisfaction among prostate cancer patients and their spouses

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