2016
DOI: 10.1002/pbc.26361
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The PETALE study: Late adverse effects and biomarkers in childhood acute lymphoblastic leukemia survivors

Abstract: The PETALE study will contribute to comprehensively characterize clinical, psychosocial, biologic, and genomic features of cALL survivors using an integrated approach. Expected outcomes include LAE early detection biomarkers, long-term follow-up guidelines, and recommendations for physicians and health professionals.

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Cited by 74 publications
(76 citation statements)
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“…They were at least 5 years postdiagnosis, without relapse and no second cancer or stem cell transplant at study enrolment. The present study was conducted as part of a larger study aiming at describing mood and quality of life in long‐term childhood ALL survivors and their families in the PETALE cohort . Two‐hundred and fifty‐one survivors and their families were contacted, 225 agreed to participate and we obtained full data from 222 survivors (response rate 88%), 209 mothers (83%), and 174 fathers (69%).…”
Section: Methodsmentioning
confidence: 82%
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“…They were at least 5 years postdiagnosis, without relapse and no second cancer or stem cell transplant at study enrolment. The present study was conducted as part of a larger study aiming at describing mood and quality of life in long‐term childhood ALL survivors and their families in the PETALE cohort . Two‐hundred and fifty‐one survivors and their families were contacted, 225 agreed to participate and we obtained full data from 222 survivors (response rate 88%), 209 mothers (83%), and 174 fathers (69%).…”
Section: Methodsmentioning
confidence: 82%
“…Participants were successfully treated for acute lymphoblastic leukemia (ALL) with Dana Farber Cancer Institute (DFCI) protocols at Sainte‐Justine University Health Center (SJUHC), PETALE Cohort . They were at least 5 years postdiagnosis, without relapse and no second cancer or stem cell transplant at study enrolment.…”
Section: Methodsmentioning
confidence: 99%
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“…As part of the PETALE study, 27 we recruited 50 adults who were survivors of childhood ALL; were at least 5 years after diagnosis; were treated with 1985 to 2005 Dana-Farber Cancer Institute ALL protocols (DFCI-ALL 87-01 to 2005-01); had no history of refractory ALL, disease recurrence, or hematopoietic stem cell transplantation; and were diagnosed between ages birth to 17 years (see Supporting Table 1). We also recruited 29 age-matched and sex-matched healthy subjects with no reported history of cancer or neurological or psychiatric disorders.…”
Section: Participantsmentioning
confidence: 99%
“…We also recruited 29 age-matched and sex-matched healthy subjects with no reported history of cancer or neurological or psychiatric disorders. 27,28 Participants had normal color vision. 1).…”
Section: Participantsmentioning
confidence: 99%