The PFO anatomy evaluation as possible tool to stratify the associated risks and the benefits arising from the closure

Fazio, Giovanni; Ferro, G; Carità, Patrizia; Lunetta, Monica; Gullotti, A.; Trapani, Renato; Fabbiano, A; Novo, Giuseppina; Novo, Salvatore

doi:10.1093/ejechocard/jeq003

Cited by 8 publications

(7 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Certainly, further studies are necessary to define in symptomatic patients the optimal therapeutic strategy, adapting it to the specific risk profile as not all the PFO could be associated to the same risk of recurrent ischemic events [26,27].…”

Section: Discussionmentioning

confidence: 99%

The percutaneous treatment of Patent Foramen Ovale, an effective and safe therapeutic choice

et al. 2013

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

The percutaneous treatment of Patent Foramen Ovale, an effective and safe therapeutic choice

et al. 2013

Self Cite

View full text Add to dashboard Cite

show abstract

“…Patients were classified into three levels: no MBs, negative test for RLS; ≤10 MBs, small or non-significant RLS; >10 MBs or significant RLS. Although there are some cut-off variations, the consensus seems to be that RLS is present if multiple MBs are detected (more than one) and is considered significant whenever more than 10 MBs are detected 21,22,23,24…”

Section: Methodsmentioning

confidence: 99%

Comparison of right-to-left shunt characteristics in cryptogenic embolic ischemic stroke and non-cardioembolic ischemic stroke

Scavasine

Chamma

Bazan

et al. 2021

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

Background: Patent foramen ovale (PFO) has been considered a potential mechanism of embolic stroke of undetermined origin. Objective: The aim of the present study was to identify the features of the right-to-left shunt (RLS) in patients with undetermined embolic ischemic stroke and compare them with those of patients with non-cardioembolic ischemic stroke. Methods: A retrospective study was conducted with 168 patients with stroke and RLS separated into the following two groups: the undetermined embolic stroke group (UES group) and non-cardioembolic stroke group (NCES group). All patients were assessed by transcranial Doppler to evaluate the presence and quantification of microembolic signals (MES) at rest and under Valsalva maneuver. Results: Of all patients evaluated in the current study, 96 were included in the UES group and 72 in the NCES group. In the UES group, 65 patients had RLS with ≥10 MES (67.7%), which was higher than that observed in the NCES group (51.4%, p=0.038). According to the moment of the cardiac cycle, 75 patients (78.1%) in the UES group had a positive test at rest compared to 42 (58.3%) in the NCES group (p=0.007). Conclusions: The current study demonstrated that almost 70% of patients with undetermined embolic stroke and PFO presented a large RLS and more than 75% had RLS at rest. These findings suggest that the size of the shunt should be taken into account when evaluating whether PFO could be a possible mechanism underlying cryptogenic stroke.

show abstract

“…The results related with the effect of closure of PFO on attacks are controversial. According to the MIST (Migraine Intervention with STARFlex Technology) study, no difference could be found in patients who underwent this procedure in the frequency of migraine attacks 6 months later compared to patients who did not underwent this procedure (34,35).…”

Section: Cardiac Diseasesmentioning

confidence: 99%

Migren ve Hastalık Birlikteliği

Bıçakçı¹

2013

npa

View full text Add to dashboard Cite

Migraine is a common neurological disorder and can be severely disabling during attacks. The highest prevalence occurs between the ages of 25 and 55 years. Prior studies have found that migraine occurs together with other illnesses at a greater coincidental rate than is seen in the general population. These occurrences are called "comorbidities". To delineate the comorbidities of migraine is important, because it can help improve treatment strategies and the understanding of the possible pathophysiology of migraine.

show abstract

The PFO anatomy evaluation as possible tool to stratify the associated risks and the benefits arising from the closure

Abstract: It is possible to suppose that not all PFO have the same prognostic value. The evaluation of two anatomical characteristics can allow to identify those foramina at higher risk and, as a consequence, the patients who could have a major benefit from the closure.

Cited by 8 publications

References 38 publications

The percutaneous treatment of Patent Foramen Ovale, an effective and safe therapeutic choice

The percutaneous treatment of Patent Foramen Ovale, an effective and safe therapeutic choice

Comparison of right-to-left shunt characteristics in cryptogenic embolic ischemic stroke and non-cardioembolic ischemic stroke

Migren ve Hastalık Birlikteliği

Contact Info

Product

Resources

About