The pharmacological activities of Albizia ferruginea and Newbouldia laevis on Pseudomonas aeruginosa, Staphylococcus aureus and Epidermophyton species

Abstract

Following studies made on the standardization of a traditional recipe made of Albizia ferruginea and Newbouldia laevis, we carried out studies on pharmacological effects on microorganisms found on dermatosis: two bacteria Staphylococcus aureus, Pseudomonas aeruginosa and three species of Epidermophyton. Materials and Methods: Following the harvest of the truck pulps of Albizia ferruginea and Newbouldia laevis at Eloundem, they were dry for a week in an ambient environment, followed by a grinding to a granular powdered form. A powder mass of 250 g was used for the extract, using a Soxhlet from BEHR LABOR-TECHNIK. Therefore, a mixture of ethanol-water in a volume ratio of 70/30 was used as a solvent. The renewal of fungi strain was made by regeneration and viability testing phase. The antifungal antivity was made using Disc diffusion method and the broth dilution method. Results: MICs were respectively: MIC was 12.5 mg/mL on Staphyloccocus aureus and 6.25 mg/mL on Pseudomonas aeruginosa; Trichophyton rubrum: 250 mg/mL for Albizia ferruginea and 250 mg/mL for Newbouldia laevis; Trichophyton interdigitale: 125 mg/mL for Albizia ferruginea and 125 mg/mL for Newbouldia laevis; Trichophyton violaceum: 125 mg/mL for Albizia ferruginea and 250 mg/mL for Newbouldia laevis. Conclusions: Our different plant extracts would be a possibility to explore in the study of in vivo antibacterial and anti-dermatophytic activities.