The Pharmacological and Phytochemical Study of Adansonia digitata

Kumar, Gautam; Kumar, Ravi; Gautam, Girendra Kumar; Rana, Harshit

doi:10.52711/2321-5836.2022.00014

Cited by 2 publications

(1 citation statement)

References 31 publications

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“…The plant has antibacterial, antiviral, antiallergic, and analgesic properties and has been used to treat specific symptoms including vomiting, heartburn, diarrhea, earaches, diabetes, arthritis, hypertension, and upper respiratory infections (Ojewole, 2002;Okwu and Nnamdi, 2011). K. pinnata has also been used as a muscle relaxant and an insecticide (Kumar et al, 2023). The leaf juice is used to treat cholera and the leaves can be fire-roasted and applied to wounds (Coutinho et al, 2021;Fernandes et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Inhibition and dissolution of calcium oxalate crystals and kidney stones by the extract of Kalanchoe pinnata

Samantha,

Shanika,

Fatema

et al. 2023

J. Med. Plants Res.

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Kalanchoe pinnata leaves are used in South Asia as a natural kidney stone treatment. In vitro studies were conducted in supersaturated and artificial urine solutions to evaluate the antiurolithic properties of K. pinnata leaf extract on calcium oxalate monohydrate (COM) and surgically extracted kidney stones. Key organic acids present in the plant extract were also examined in artificial urine to investigate inhibition of kidney stone formation. Crystals harvested from inhibition and dissolution experiments were characterized by mass change, Fourier transform infrared (FTIR) spectroscopy, thermogravimetric analysis (TGA), scanning electron microscopy (SEM), redox titrations, and conductivity measurements. K. pinnata plant extract significantly inhibited crystal growth mechanisms depending on the extract concentration and supported dissolution. Crystal growth in supersaturated solutions and artificial urine was inhibited by 41 and 15 wt%, respectively, and COM and kidney stone mass decreased by 30 and 18 wt% after five extract washes. Active compounds identified in K. pinnata extract are malic, p-hydroxybenzoic, syringic, and caffeic acids, each demonstrated 2.70 to 4.65 wt% inhibition, which cumulatively accounts for the 15% inhibition observed in synthetic urine. This preliminary study demonstrates that the organic acid content of K. pinnata leaf extract is a crucial component for antiurolithic activity.

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Section: Introductionmentioning

confidence: 99%

Inhibition and dissolution of calcium oxalate crystals and kidney stones by the extract of Kalanchoe pinnata

Samantha,

Shanika,

Fatema

et al. 2023

J. Med. Plants Res.

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Nutritional and pharmacological attributes of baobab fruit pulp

Abdulwaliyu,

Arekemase,

Batari

et al. 2024

Food Prod Process and Nutr

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Foods, especially medicinal foods, play a vital role in providing nutrients for healthy growth and in the management of clinical disorders. Unfortunately, half of the global population lacks access to affordable healthcare and a nutritious diet. Therefore, it is important to identify traditional and scientifically proven therapeutic foods for disease management and the prevention of micronutrient deficiencies. Baobab, one of nature ‘s gifts to mankind, is the focus of this study. The aim was to provide an overview of its medicinal and nutritional benefits through a literature search. Research indicates that baobab fruit pulp is a rich source of fiber, calcium, magnesium, potassium, and notably vitamin C, about five to 10 times the content found in oranges. Additionally, baobab fruit pulp has been found to possess various therapeutic properties, including antibacterial, anti-inflammatory, antidiabetic, anticancer, and antiulcer characteristics. Furthermore, it is considered safe for consumption. These findings emphasize the importance of increasing baobab plantations and raising public awareness about the health benefits of the fruit through educational initiatives. Further research is necessary to explore the potential of baobab fruit pulp as a therapeutic agent for improved health. Graphical Abstract

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The Pharmacological and Phytochemical Study of Adansonia digitata

Cited by 2 publications

References 31 publications

Inhibition and dissolution of calcium oxalate crystals and kidney stones by the extract of Kalanchoe pinnata

Inhibition and dissolution of calcium oxalate crystals and kidney stones by the extract of Kalanchoe pinnata

Nutritional and pharmacological attributes of baobab fruit pulp

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