2015
DOI: 10.1515/med-2015-0077
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The pharmacological research of Tek-1 relevance to anti-neuroinflammation, a candidate compound based on Telmisartan

Abstract: In this paper, BV-2 mouse small glial cell inflammation model induced by LPS is established. The experiment used 0.1–10 μM of telmisartan and Tek-1 to incubate with small glial cell and used telmisartan and Tek-1 to incubate with PPAR gamma special heterosexual antagonistic anti-agent GW9662. The article used ELISA method to dectect TNF-a effect on small glial cell for telmisartan and Tek-1. The article used real-time quantitative PCR method to dectect mRNA level expression effect of CD11b, CD16 and iNOS on sm… Show more

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