The Phenolic, Flavonoid, and Anthocyanin Content From Methanol Extract of Senggani Fruit and Its Antioxidant Activity

Purwaningsih, Indah; Fathiah, Fathiah; Amaliyah, Nurul; Kuswiyanto, Kuswiyanto

doi:10.30598//ijcr.2023.10-pur

Cited by 5 publications

(4 citation statements)

References 30 publications

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“…However, steroids were not detected in the extract. The results of this study were the same as those conducted by (Purwaningsih et al, 2023). Namely, steroids were not detected in the methanol extract of the senggani fruit.…”

Section: Phytochemical Screening Of Bhee Fruit Extract (Melastoma Sp)supporting

confidence: 82%

Phytochemical Screening and Blood Glucose Level Effects of Bhee Fruit Extract (Melastoma sp) on Diabetic Mice

Rinawati,

Muhsin,

Sari

et al. 2023

J-Kesmas

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Diabetes is a non-communicable disease among the highest causes of death worldwide, including in Indonesia. Factors that cause diabetes include pancreatic β-cell damage, genetic factors, and an unhealthy lifestyle. Diabetes is characterized by high blood glucose levels (hyperglycemia) beyond normal limits. Hyperglycaemia can be treated using synthetic chemical drugs or insulin therapy, which has adverse long-term effects. The community believes herbal medicine is an alternative diabetes treatment. Melastoma sp is a plant that has the potential as an antidiabetic agent. This study aimed to determine the effectiveness of ethanol extract of Bhee fruit (Melastoma sp) on blood glucose levels of diabetic mice. This study is a laboratory experiment using laboratory animals. The mice were divided into seven treatment groups with three replicates: KN (normal control), KP (treatment control), KD (diabetes control), KO (drug control), P1 (treatment dose of 100 mg/kgBB extract), P2 (treatment dose of 200 mg/kgBB extract), and P3 (treatment dose of 400 mg/kgBB extract). The study's results, the administration of doses of ethanol extract of the fruit 100, 200, and 300 mg /kgBB for 14 days reduced glucose levels in diabetic mice. However, they could not exceed the ability metformin at a dose of 500 mg/kgBB.

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Section: Phytochemical Screening Of Bhee Fruit Extract (Melastoma Sp)supporting

confidence: 82%

Phytochemical Screening and Blood Glucose Level Effects of Bhee Fruit Extract (Melastoma sp) on Diabetic Mice

Rinawati,

Muhsin,

Sari

et al. 2023

J-Kesmas

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“…This process limits the exposure of anthocyanins to atmospheric conditions and light, thereby reducing their susceptibility to oxidative degradation. In addition, it is noteworthy that, despite the potential for higher temperature application in anthocyanin extraction, the prevailing majority of researchers have refrained from utilizing temperatures exceeding 40 • C in the course of their experiments involving this methodology [18]. Nevertheless, it is imperative to acknowledge certain limitations associated with this method, particularly its elevated production costs.…”

Section: Supercritical Fluid Extraction Methodsmentioning

confidence: 99%

“…Furthermore, given the heightened stability of anthocyanins in acidic environments, acidic solutions are typically employed as extractants. Methanol and citric acid have been determined as the optimal extractant choices [18]. Nevertheless, the drawbacks of organic solvents, including heightened environmental impact and challenging recovery processes, have spurred the predominant utilization of water-based extraction methods in practical applications.…”

Section: Solvent Extractionmentioning

confidence: 99%

“…Senggani fruit minimize damage or loss of compounds; low yield, low product quality, high energy input, time-consuming, need substantial amounts of solvents [18] Ultrasonic extraction rose flower petal significantly improve anthocyanins extraction rate, efficient; require complex and expensive equipment, difficult to realize industrialization [19,20] Microwave extraction the fruits of Syzygium nervosum (ma-kiang in Thai)…”

Section: Solvent Extractionmentioning

confidence: 99%

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Advances in the Preparation, Stability, Metabolism, and Physiological Roles of Anthocyanins: A Review

Li,

Zhang,

Wang

et al. 2023

Foods

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Anthocyanins are natural flavonoid polyphenolic compounds widely found in fruits and vegetables. They exhibit antioxidant properties and prophylactic effects in the immune and cardiovascular systems, confer protection against cancer, and contribute to the prevention of cardiovascular diseases. Thus, their incorporation into functional foods, pharmaceuticals, supplements, and cosmetic formulations aims at promoting human well-being. This review comprehensively outlined the structural attributes of anthocyanins, expanding upon diverse methodologies employed for their extraction and production. Additionally, the stability, metabolic pathways, and manifold physiological functions of anthocyanins were discussed. However, their constrained fat solubility, susceptibility to instability, and restricted bioavailability collectively curtail their applicability and therapeutic efficacy. Consequently, a multidimensional approach was imperative, necessitating the exploration of innovative pathways to surmount these limitations, thereby amplifying the utilitarian significance of anthocyanins and furnishing pivotal support for their continual advancement and broader application.

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The Flavonoids, Phenolics, and Antioxidant Activity from Ethanol Extract of Fibraurea tinctoria Lour

Fathiah,

Purwaningsih,

Suryana

2024

j. info kesehat.

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Oxidative stress has long been associated with increased risk for several diseases. Antioxidant is a molecule that inhibits the oxidation of other molecules and delays or prevents oxidative damage. Natural phenolic and flavonoid compounds are plant secondary metabolites directly contributing to antioxidant activity. Fibraurea tinctoria Lour, often called the yellow root, is a plant that has long been known in the traditional medicine of the native tribes of West Kalimantan to treat several diseases, including malaria, jaundice, and diabetes. This study aimed to quantify the total phenolic (TPC) and flavonoid (TFC) contents and antioxidant activity of the ethanol extract of yellow root stems. Yellow root stems were extracted by maceration in 96% ethanol for four days. The total phenolic, flavonoid, and antioxidant activities were measured using the Folin-Ciocalteu, AlCl3, and DPPH methods. Phytochemical screening showed that the ethanol extract of yellow root stems contains phenolics, flavonoids, alkaloids, saponins, tannins, and steroids/triterpenoids. The total phenol and flavonoid contents were 40.2 mg GAE/g extract and 61.2 mg QE/g extract, respectively. The ethanol extract of yellow root stems showed moderate DPPH scavenging activity, with an IC50 of 152.13 ppm. From this study, it can be concluded that this plant could be a potential source of natural antioxidants.

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The Phenolic, Flavonoid, and Anthocyanin Content From Methanol Extract of Senggani Fruit and Its Antioxidant Activity

Cited by 5 publications

References 30 publications

Phytochemical Screening and Blood Glucose Level Effects of Bhee Fruit Extract (Melastoma sp) on Diabetic Mice

Phytochemical Screening and Blood Glucose Level Effects of Bhee Fruit Extract (Melastoma sp) on Diabetic Mice

Advances in the Preparation, Stability, Metabolism, and Physiological Roles of Anthocyanins: A Review

The Flavonoids, Phenolics, and Antioxidant Activity from Ethanol Extract of Fibraurea tinctoria Lour

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