Tourette Syndrome 2013
DOI: 10.1093/med/9780199796267.003.0002
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The Phenomenology of Attention-Deficit/Hyperactivity Disorder in Tourette Syndrome

Abstract: This chapter focuses on the complex epidemiological and phenomenological aspects of attention-deficit/hyperactivity disorder (ADHD) in Tourette syndrome (TS). Research on this topic is relatively recent and has elucidated the importance of comorbidity in TS and the need for an early assessment for ADHD in TS. Several observational studies confirmed that ADHD is the most common comorbidity in TS (present in about 60% of cases), possibly anticipating TS onset and influencing the male gender predominance of TS. A… Show more

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Cited by 33 publications
(23 citation statements)
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“…These include but are not limited to learning disabilities, language disorder, disruptive behavior, anxiety, mood disorders, tic disorders, seizures, autism spectrum disorder, developmental coordination disorder, and sleep disorders. [50][51][52][53][54][55][56][57][58][59][60][61][62][63][64][65][66] In some cases, the presence of a comorbid condition will alter the treatment of ADHD.…”
Section: Kasmentioning
confidence: 99%
“…These include but are not limited to learning disabilities, language disorder, disruptive behavior, anxiety, mood disorders, tic disorders, seizures, autism spectrum disorder, developmental coordination disorder, and sleep disorders. [50][51][52][53][54][55][56][57][58][59][60][61][62][63][64][65][66] In some cases, the presence of a comorbid condition will alter the treatment of ADHD.…”
Section: Kasmentioning
confidence: 99%
“…Some study groups recently proposed the idea of a heterogeneous spectrum as a TS phenotype with associated disorders rather than a unitary condition. 18,23,24 The clinical spectrums of TS þ ADHD tend to overlap, especially in boys, suggesting a common pathophysiological basis (for reviews see, e.g., Freeman et al, 21 Cavanna and Rickards, 25 and Rothenberger and Roessner 26 ). Regarding TS þ ADHD as a comorbid condition, evidence points toward an, sometimes, increased risk for disruptive and aggressive (externalizing) behaviors instead of increased tic severity.…”
Section: Comorbidity and Psychopathological Issuesmentioning
confidence: 99%
“…The rates are much lower among children with chronic motor or vocal tic disorder [7]. The prevalence of ADHD in patients with TS who reach clinical attention may be even higher [11, 29]. Based on the results of a longitudinal follow-up study of 65 individuals with TS and 65 matched community controls without tic or OCD symptoms, higher levels of ADHD severity in late adolescence are associated with a significantly lower level of global functioning [29].…”
Section: Comorbid Conditionsmentioning
confidence: 99%
“…Why do tics remit, or at least improve dramatically, in most individuals by the end of the second decade of life [13, 15 26]? Why do ADHD and tic-related OCD occur as commonly as they do [4, 11, 12, 29]? Why are these disorders so much more common in individuals with TS versus a chronic motor tic disorder [7]?…”
Section: Unanswered Questions An Agenda For Future Researchmentioning
confidence: 99%