The physiology and management of childhood asthma

Psychological factors in asthma: a review of their aetiological and therapeutic significance

“…This definition has the advantage of allowing physiological measurements of airway obstruction to be used as a basis of diagnosis, but it has the disadvantage that it tells us nothing about the asthmatic subject when he is free from attacks. It was Jones (1966Jones ( , 1971) who first attempted to characterize this instability of the bronchial tract and to give some measure to it, pointing out that tests of ventilatory function such as the forced expiratory volume in one second (FEV1) may be normal at times in some subjects with severe asthma. He had previously shown (Jones, Buston & Wharton, 1962) that exercise in asthmatics is followed by bronchoconstriction as indicated by a fall in the FEV1, whilst maximum bronchodilatation as indicated by a rise in FEV1, could be produced by inhalation of isoprenaline followed by 1 min exercise (Jones, Wharton & Buston, 1963).…”

Symptom Formation Reconsidered in Psychosomatic Terms

“…In childhood asthma, for example, this is expressed as excessive lability of the bronchial system (Jones, 1971;Pinkerton, 1967); in migraine, as presumed neurovascular anomaly of the intracranial microcirculation; in atopic eczema, as constitutional hypersensitivity of the epidermis; in spastic colon, as neurohumoral hyperirritability of the large gut (Chaudhary and Truelove, 1961); while in peptic ulcer, it is reflected in raised serum pepsinogen levels ( Weiner et al, 1957).…”

Paediatrics and child psychiatry. The case for collaboration.

“…Thus in asthma, though the basis is an immuno-physiological substrate of enhanced bronchial lability (Jones, 1971), additional factors are required to induce an actual attack. These include exposure to certain allergens in appropriately sensitive subjects; intercurrent chest infection if ventilatory function is already depressed; and on occasion, the prevailing aura of parent/child interaction.…”